Department of Physical Medicine and Rehabilitation, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
J Clin Rheumatol. 2013 Sep;19(6):341-3. doi: 10.1097/RHU.0b013e31829ce57c.
Prolactin-secreting adenomas represent nearly 40% to 60% of all pituitary adenomas. Prolactin inhibits the secretion of gonadotropin-releasing hormone that is responsible for the synthesis and secretion of gonadotropins. Sex steroids have an important effect on the regulation of bone metabolism in men. Decreased libido and impotence are the most common presenting symptoms of hyperprolactinemia in males. These symptoms are easily neglected by both patients and some physicians. We present a 22-year-old man with multiple osteoporotic fractures associated with prolactinoma despite the use of teriparatide for 18 months. We emphasize and highlight the importance of hyperprolactinemia and fractures caused by high prolactin levels.
催乳素分泌腺瘤占所有垂体腺瘤的近 40%至 60%。催乳素抑制促性腺激素释放激素的分泌，后者负责促性腺激素的合成和分泌。性激素对男性骨代谢的调节有重要影响。性欲减退和阳萎是男性高催乳素血症最常见的表现症状。这些症状很容易被患者和一些医生忽视。我们报告了 1 例 22 岁男性患者，尽管使用特立帕肽治疗 18 个月，但仍患有催乳素瘤导致的多发性骨质疏松性骨折。我们强调并突出了高催乳素血症和高催乳素水平引起的骨折的重要性。
