Takano T, Okisaka S, Hamanaka T, Ishida T, Hara J
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
Nippon Ganka Gakkai Zasshi. 1990 Apr;94(4):424-31.
A case of a 66-year-old woman suffering from polymyalgia rheumatica with necrotizing scleritis followed central retinal artery occlusion in the left eye was studied clinico-pathologically. The left eye was enucleated because of severe pain in spite of the steroid therapy, and was examined histopathologically. The necrotic granulomatous changes of the deep sclera in the ciliary body and peripheral fundus were observed. Lymphocytes, plasma cells and epitheloid cells infiltrated in the central retinal artery at the papilla. It seemed that subconjunctival injection of steroid had induced scleral necrosis. When scleritis is very severe, it might be suggested that systemic steroid should be given in large suppressive doses.
对一名66岁患有风湿性多肌痛伴坏死性巩膜炎的女性患者进行了临床病理研究，该患者随后左眼发生视网膜中央动脉阻塞。尽管进行了类固醇治疗，但由于左眼剧痛，遂将其摘除并进行组织病理学检查。观察到睫状体和周边眼底深层巩膜有坏死性肉芽肿改变。视乳头处视网膜中央动脉有淋巴细胞、浆细胞和上皮样细胞浸润。结膜下注射类固醇似乎诱发了巩膜坏死。当巩膜炎非常严重时，可能提示应给予大剂量的全身性类固醇进行抑制治疗。
