Kikuchi Shogo
Department of Public Health, Aichi Medical University School of Medicine.
Nihon Rinsho. 2013 Aug;71(8):1331-6.
Progress in sanitary conditions, especially development of clean water supply for these 50 years has been reducing prevalence of Helicobacter pylori infection in Japan. The reduction in corporation with a less intake of highly salted foods and probably infection at later ages decreases prevalence and/or severity of gastric mucosal atrophy. Consequently, incidence of gastric cancer has been decreasing. However, it was unveiled that those with H. pylori infection and gastric mucosal atrophy have high risk of gastric cancer even after successful eradication of the infection, which still remains as a problem.
卫生条件的改善，尤其是这50年来清洁供水的发展，一直在降低日本幽门螺杆菌感染的患病率。减少高盐食物的摄入量以及可能在较晚年龄感染，这两者共同作用降低了胃黏膜萎缩的患病率和/或严重程度。因此，胃癌的发病率一直在下降。然而，有研究表明，即使成功根除幽门螺杆菌感染，那些感染幽门螺杆菌且有胃黏膜萎缩的人患胃癌的风险仍然很高，这仍是一个问题。
