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直接皮层电刺激选择性干扰人类对大小的表示。

Selective interference with the representation of size in the human by direct cortical electrical stimulation.

出版信息

J Cogn Neurosci. 1992 Fall;4(4):337-44. doi: 10.1162/jocn.1992.4.4.337.

DOI:10.1162/jocn.1992.4.4.337
PMID:23968127
Abstract

A specific category in human cognition, size representation, was disrupted by the application of cortical electrical interference through a recently modified technique involving implantation of indwelling subdural electrode arrays. When subjected to electrical stimulation at a specific site, the subject was unable to access size information when questioned verbally, but showed no deficit if the size discrimination was presented visually. Verbal questions about size were answered correctly when the patient was not subjected to cortical interference. Other measures of verbal and visual comprehension for the categories of color, shape, orientation, movement, texture, and structure, tested under cortical interference, were normal. This clear-cut distinction between verbal and visual access to information about size, shown by a reversible block at a known and anatomically circumscribed site, provides further evidence that higher order neural processing is categorically represented.

摘要

人类认知的一个特定类别,即大小表示,被最近修改的技术应用于皮质电干扰所破坏,该技术涉及植入留置的硬脑膜下电极阵列。当在特定部位接受电刺激时,被试在被口头提问时无法获得大小信息,但如果大小辨别以视觉呈现则没有缺陷。当患者不受皮质干扰时,关于大小的口头问题回答正确。在皮质干扰下测试的颜色、形状、方向、运动、纹理和结构等类别的言语和视觉理解的其他措施正常。在一个已知的、解剖上限定的部位的可逆阻断下,大小信息的言语和视觉获取之间的这种明显区别,进一步证明了高级神经处理是按类别表示的。

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