Departments of Psychobiology and of Anatomy and Neurobiology, University of California, Irvine.
J Cogn Neurosci. 1989 Winter;1(1):3-11. doi: 10.1162/jocn.1989.1.1.3.
The demonstration that functional somatotopic maps within the adult neocortex undergo some degree of reorganization following peripheral injury has aroused considerable interest. The evidence for such reorganization in the rat and monkey is reviewed and it is concluded that in both species there is good evidence for limited functional map reorganization in the adult neocortex following peripheral injury. The significance of such functional map reorganization, particularly in terms of whether or not cortical maps are continuously modifiable throughout life, is discussed. It is concluded that the current evidence for map reorganization is best interpreted in terms of the unmasking of preexisting neuronal circuits rather than as evidence of dynamic cortical selection processes.
成人新皮层内的功能性躯体感觉区在受到外周损伤后会发生一定程度的重组，这一发现引起了广泛关注。本文回顾了在大鼠和猴子中此类重组的证据，并得出结论，在这两个物种中，外周损伤后成人新皮层的功能区图确实存在一定程度的有限重组。本文还讨论了这种功能区图重组的意义，特别是在皮质区是否可以在整个生命周期中持续改变的问题。结论认为，目前关于图谱重组的证据最好用预先存在的神经元回路的揭示来解释，而不是用动态皮质选择过程的证据来解释。
