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情况并非看上去那么糟糕:新疫苗上市时医生预测其临床应用的能力。

Things are not as bad as they seem: physicians' ability to predict their clinical practice when a new vaccine becomes available.

作者信息

Seewald Laura, Hurley Laura, Crane Lori A, Dong Fran, Stokley Shannon, Daley Matthew F, Barrow Jennifer, Babbel Christine, Dickinson L Miriam, Kempe Allison

机构信息

Children's Outcomes Research Program, Children's Hospital Colorado, Aurora, CO.

出版信息

Healthc Policy. 2013 May;8(4):71-85.

Abstract

Survey results regarding primary care physicians' likelihood of recommending a new vaccine were compared before and after the vaccine was licensed by the Food and Drug Administration for three new vaccines: herpes zoster (HZ), human papillomavirus (HPV) and rotavirus (RV), using physician networks representative of United States physicians. The main purpose of this study was to determine (a) how accurately physicians predict their eventual vaccine recommendations and the barriers they will experience in delivering the new vaccine and (b) whether physicians shift towards more or less strongly recommending a new vaccine from pre- to post-licensure. Responses from 284, 152 and 184 physicians were analyzed for the three vaccines, respectively. For all vaccines, there was a significant association between physicians' pre- and post-licensure recommendations (p<0.05). When responses changed from pre- to post-licensure, physicians tended to recommend a given vaccine more strongly than they had anticipated pre-licensure. Before vaccine availability, physicians tended to predict greater barriers to vaccine delivery than they eventually experienced. Surveys are useful for predicting physician practices, but may provide a slightly pessimistic view of physician adoption of new vaccines. Such data can be helpful in devising strategies to encourage vaccine delivery by physicians.

摘要

使用代表美国医生的医生网络,比较了在三种新疫苗(带状疱疹疫苗(HZ)、人乳头瘤病毒疫苗(HPV)和轮状病毒疫苗(RV))获得美国食品药品监督管理局(Food and Drug Administration)许可之前和之后,关于初级保健医生推荐新疫苗可能性的调查结果。本研究的主要目的是确定:(a)医生对其最终疫苗推荐的预测准确性以及他们在提供新疫苗时将遇到的障碍;(b)从疫苗许可前到许可后,医生对新疫苗的推荐倾向是更强还是更弱。分别对284名、152名和184名医生针对这三种疫苗的回复进行了分析。对于所有疫苗,医生在疫苗许可前后的推荐之间存在显著关联(p<0.05)。当回复从疫苗许可前变为许可后时,医生倾向于比他们在疫苗许可前所预期的更强烈地推荐某种疫苗。在疫苗可用之前,医生倾向于预测疫苗接种的障碍比他们最终实际遇到的更大。调查对于预测医生的行为是有用的,但可能对医生采用新疫苗的情况提供了略微悲观的看法。此类数据有助于制定鼓励医生接种疫苗的策略。

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本文引用的文献

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The HPV vaccine controversy.人乳头瘤病毒疫苗争议
Virtual Mentor. 2012 Jan 1;14(1):39-49. doi: 10.1001/virtualmentor.2012.14.1.msoc1-1201.
4
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Ann Intern Med. 2010 May 4;152(9):555-60. doi: 10.7326/0003-4819-152-9-201005040-00005.

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