大鼠、豚鼠和兔组织中烟酰胺腺嘌呤二核苷酸磷酸苹果酸脱氢酶、磷酸烯醇式丙酮酸羧激酶和丙酮酸羧化酶的活性及细胞内分布
The activities and intracellular distribution of nicotinamide-adenine dinucleotide phosphate-malate dehydrogenase, phosphoenolpyruvate carboxykinase and pyruvate carboxylase in rat, guinea-pig and rabbit tissues.
作者信息
Saggerson D, Evans C J
出版信息
Biochem J. 1975 Feb;146(2):329-32. doi: 10.1042/bj1460329.
Abstract
- Measurements are presented of the activity and intracellular distribution of phosphoenolypruvate carboxykinase, pyruvate carboxylase and NADP-malate dehydrogenase in rat, guinea-pig and rabbit liver and kidney cortex, together with previously obtained measurements of these enzymes in adipose tissue. 2. In all three tissues pyruvate carboxylase activity was greatest in the rat and lowest in the rabbit. 3. Guinea pig and rabbit were very similar to each other with respect to the extramitochondrial-mitochondrial distribution of phosphoenolpyruvate carboxykinase in all three tissues. 4. NADP-malate dehydrogenase was present in all three tissues in the rat, present in kidney cortex and adipose tissue in the guinea pig and absent from all tissues examines in the rabbit.
摘要
- 本文给出了大鼠、豚鼠和兔肝脏及肾皮质中磷酸烯醇式丙酮酸羧激酶、丙酮酸羧化酶和NADP-苹果酸脱氢酶的活性及细胞内分布情况，以及之前在脂肪组织中获得的这些酶的测量数据。2. 在所有这三种组织中，丙酮酸羧化酶活性在大鼠中最高，在兔中最低。3. 在所有这三种组织中，豚鼠和兔在磷酸烯醇式丙酮酸羧激酶的线粒体外-线粒体分布方面彼此非常相似。4. NADP-苹果酸脱氢酶在大鼠的所有三种组织中均存在，在豚鼠的肾皮质和脂肪组织中存在，而在兔的所有检测组织中均不存在。
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