Huffman D C, Holmes Erin R
Research and Education Foundation, American College of Apothecaries, Bartlett, Tennessee.
Int J Pharm Compd. 2008 Jan-Feb;12(1):74-82.
Pharmacy compounding is re-emerging as a critical area of pharmacy practice. This re-emergence has generated considerable discussion among stakeholders of the pharmacy profession about how pharmacy compounding is best regulated to ensure the safety and efficacy of compounded preparations. In light of this discussion, the American College of Apothecaries conducted a survey in August 2006 that was sent to compounding pharmacists, the list of which was provided by the International Journal of Pharmaceutical Compounding. The purpose of the survey was to (1)assess the safety and efficacy of compounded preparations as reported by compounding pharmacists, (2)describe the types of compounding and other professional services that are offered by these pharmacists, (3)describe selected business information for compounding pharmacies, and (4)monitor changes in the compounding pharmacy landscape since the 2005 National Survey of Compounding Pharmacists, the results of which were published in the November/December 2006 issue of the International Journal of Pharmaceutical Compounding. State boards of pharmacy were surveyed for reports of problems related to instability of compounded preparations and adverse reactions caused by compounded preparations. Data trends in this study are similar to those reported in the 2005 survey, also conducted by the American College of Apothecaries. Repsondents reported relatively few adverse events caused by compounded preparations. These respondents, many of whom are independent pharmacists, offer a variety of compounding, professional, and patient care services. Of 18 responding state boards of pharmacy, four noted reports of compounding problems in their state.
药学配制正重新成为药学实践的一个关键领域。这种重新兴起在药学专业的利益相关者中引发了大量讨论，内容涉及如何对药学配制进行最佳监管，以确保配制制剂的安全性和有效性。鉴于此讨论，美国药剂师学会于2006年8月进行了一项调查，问卷发送给了配制药剂师，其名单由《国际药学配制杂志》提供。该调查的目的是：（1）评估配制药剂师报告的配制制剂的安全性和有效性；（2）描述这些药剂师提供的配制类型及其他专业服务；（3）描述配制药房的部分商业信息；（4）监测自2005年全国配制药剂师调查以来配制药房格局的变化，该调查结果发表在《国际药学配制杂志》2006年11/12月期上。对各州药房委员会进行了调查，以获取与配制制剂稳定性问题及配制制剂引起的不良反应相关的报告。本研究中的数据趋势与美国药剂师学会2005年进行的调查所报告的趋势相似。受访者报告称，由配制制剂引起的不良事件相对较少。这些受访者中有许多是独立药剂师，他们提供各种配制、专业和患者护理服务。在18个回复的州药房委员会中，有4个提到了本州存在配制问题的报告。
