Quality-control analytical methods: homogeneity of dosage forms.

Content uniformity is the degree of consistency in the amount of the drug substance among dosage units. There are two ways to determine content uniformity according to United States Pharmacopeial Chapter 905: by means of Content Uniformity or Weight Variation methods. It is essenetial that compounding pharmacists know the different methods, how they work, and when to use each method to determine the content uniformity of their individual dosages.