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在图案化磁场短暂刺激期间黑色素瘤细胞的光子发射:其来源是否与膜内的旋转扩散相关联?

Photon emission from melanoma cells during brief stimulation by patterned magnetic fields: is the source coupled to rotational diffusion within the membrane?

作者信息

Dotta Blake T, Lafrenie Robert M, Karbowski Lukasz M, Persinger Michael A

机构信息

Biomolecular Sciences Program, Laurentian University, Sudbury, Ontario, P3E 2C6, Canada.

出版信息

Gen Physiol Biophys. 2014;33(1):63-73. doi: 10.4149/gpb_2013066. Epub 2013 Aug 23.

Abstract

If parameters for lateral diffusion of lipids within membranes are macroscopic metaphors of the angular magnetic moment of the Bohr magneton then the energy emission should be within the visible wavelength for applied ~1 µT magnetic fields. Single or paired digital photomultiplier tubes (PMTs) were placed near dishes of ~1 million B16 mouse melanoma cells that had been removed from incubation. In very dark conditions (10(-11) W/m(2)) different averaged (RMS) intensities between 5 nT and 3.5 µT were applied randomly in 4 min increments. Numbers of photons were recorded directly over or beside the cell dishes by PMTs placed in pairs within various planes. Spectral analyses were completed for photon power density. The peak photon emissions occurred around 1 µT as predicted by the equation. Spectra analyses showed reliable discrete peaks between 0.9 and 1.8 µT but not for lesser or greater intensities; these peak frequencies corresponded to the energy difference of the orbital-spin magnetic moment of the electron within the applied range of magnetic field intensities and the standard solution for Rydberg atoms. Numbers of photons from cooling cells can be modified by applying specific intensities of temporally patterned magnetic fields. There may be a type of "cellular" magnetic moment that, when stimulated by intensity-tuned magnetic fields, results in photon emissions whose peak frequencies reflect predicted energies for fundamental orbital/spin properties of the electron and atomic aggregates with large principal quantum numbers.

摘要

如果膜内脂质横向扩散的参数是玻尔磁子角磁矩的宏观隐喻,那么对于施加的约1微特斯拉磁场,能量发射应在可见光波长范围内。将单个或成对的数字光电倍增管(PMT)放置在从培养箱中取出的约100万个B16小鼠黑色素瘤细胞培养皿附近。在非常黑暗的条件下(10^(-11) W/m²),以4分钟为增量随机施加5纳特斯拉至3.5微特斯拉之间的不同平均(均方根)强度。通过放置在不同平面内成对的PMT直接记录细胞培养皿上方或旁边的光子数。对光子功率密度进行了光谱分析。正如方程所预测的,峰值光子发射出现在约1微特斯拉附近。光谱分析表明,在0.9至1.8微特斯拉之间存在可靠的离散峰值,但在较小或较大强度下则没有;这些峰值频率对应于在施加的磁场强度范围内电子的轨道 - 自旋磁矩的能量差以及里德堡原子的标准解。通过施加特定强度的时间模式磁场,可以改变来自冷却细胞的光子数。可能存在一种“细胞”磁矩,当受到强度调谐磁场刺激时,会导致光子发射,其峰值频率反映了具有大主量子数的电子和原子聚集体的基本轨道/自旋特性的预测能量。

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