Joshi Manavi, Basra Amardeep, McCormick Claire, Webb Helen, Pakianathan Mark
St George's University of London, London, UK.
Int J STD AIDS. 2014 Jan;25(1):67-9. doi: 10.1177/0956462413491734. Epub 2013 Jul 11.
Post-exposure prophylaxis after sexual exposure (PEPSE) awareness was audited in an HIV-positive cohort. A total of 403 out of 828 (48.7%) patients were PEPSE aware. Patients diagnosed post-2006 were more PEPSE aware; 57.2% vs. 44.2% (p = 0.0004). Men who have sex with men (MSM) were more PEPSE aware; 65.8% vs. 39.1% in heterosexuals (p < 0.0001).Younger patients, 68.1% aged 19-34 were PEPSE aware vs. 45.7% in those >35 years (p < 0.0001). In the 534 patients reporting sexual activity within the last year, awareness was 57.5%. In the 216 patients 'sometimes' or 'never' using condoms, awareness was 42.6%. In the 78 (9.4%) patients with detectable viral loads (>400 copies/mL), awareness was 64.1%. Overall, PEPSE awareness was unexpectedly low. MSM, younger patients, and those diagnosed after 2006 were significantly more likely to be PEPSE aware. More than one in three patients with detectable viraemia were PEPSE unaware.
在一个HIV阳性队列中对性暴露后预防（PEPSE）的知晓情况进行了审计。828名患者中有403名（48.7%）知晓PEPSE。2006年后诊断的患者对PEPSE的知晓率更高；分别为57.2%和44.2%（p = 0.0004）。男男性行为者（MSM）对PEPSE的知晓率更高；为65.8%，而异性恋者为39.1%（p < 0.0001）。较年轻的患者，19 - 34岁年龄段中有68.1%知晓PEPSE，而35岁以上者为45.7%（p < 0.0001）。在过去一年报告有性行为的534名患者中，知晓率为57.5%。在216名“有时”或“从不”使用避孕套的患者中，知晓率为42.6%。在78名（9.4%）病毒载量可检测到（>400拷贝/mL）的患者中，知晓率为64.1%。总体而言，PEPSE知晓率出乎意料地低。MSM、较年轻的患者以及2006年后诊断的患者更有可能知晓PEPSE。超过三分之一病毒血症可检测到的患者不知道PEPSE。
