Carne C A, Gibbs J, Delaney A, Sonnex C, Verlander N Q, Smielewska A, Skeggs E, Bentley N, Jalal H
Department of Genitourinary Medicine, Clinic 1A, Box 38, Addenbrookes Hospital, Cambridge University Hospitals NHS Trust, UK.
Int J STD AIDS. 2013 Apr;24(4):273-7. doi: 10.1177/0956462412472306.
We conducted a study of the prevalence, clinical features and microscopy findings, by retrospective case-notes survey, of six non-viral organisms, among 1718 attendees at a genitourinary (GU) medicine clinic in England. An in-house assay for six non-viral infections was used and quantitation of ureaplasmas performed. The prevalences of the six organisms were: Chlamydia trachomatis (CT), 7.1%; Neisseria gonorrhoeae (NG), 0.6%; Mycoplasma genitalium (MG), 1.0%; Trichomonas vaginalis, 0.2%; Ureaplasma urealyticum, 16.1%; Ureaplasma parvum, 35.6%. Among men (but not women) there were significantly raised odds ratios compared with that for U. parvum, for the symptom of discharge with CT, 7.30; MG, 6.43; NG 19.29; dysuria with CT, 5.89 and MG, 5.95; and the microscopy finding of >4 pus cells per high power field with: CT, 7.22; MG, 4.58 and NG 22.31. Evaluation of a possible link between quantitation of U. urealyticum and urethritis did not confirm research findings elsewhere.
我们通过回顾性病例记录调查，对英格兰一家泌尿生殖医学诊所的1718名就诊者中的六种非病毒病原体的患病率、临床特征和显微镜检查结果进行了研究。采用了一种针对六种非病毒感染的内部检测方法，并对脲原体进行了定量分析。这六种病原体的患病率分别为：沙眼衣原体（CT），7.1%；淋病奈瑟菌（NG），0.6%；生殖支原体（MG），1.0%；阴道毛滴虫，0.2%；解脲脲原体，16.1%；微小脲原体，35.6%。在男性中（女性则不然），与微小脲原体相比，CT导致的分泌物症状的比值比显著升高，为7.30；MG导致的为6.43；NG导致的为19.29；CT导致的排尿困难的比值比为5.89，MG导致的为5.95；显微镜检查发现每高倍视野有>4个脓细胞的情况中，CT导致的比值比为7.22；MG导致的为4.58，NG导致的为22.31。对解脲脲原体定量与尿道炎之间可能存在的联系进行评估，并未证实其他地方的研究结果。
