恶性周围神经鞘膜瘤：CT与MRI表现

Sperandio Massimiliano, Di Poce Isabelle, Ricci Aurora, Di Trapano Roberta, Costanzo Elisa, Di Cello Pierfrancesco, Pelle Fabio, Izzo Luciano, Simonetti Giovanni

Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiation Therapy, University Hospital Tor Vergata, Viale Oxford, 81-00133 Rome, Italy.

Case Rep Radiol. 2013;2013:517879. doi: 10.1155/2013/517879. Epub 2013 Jul 18.

Malignant peripheral nerve sheath tumour (MPNST) is extremely rare malignancy in the general population, occurring more frequently in patients with Neurofibromatosis type 1 (NF1). In the literature five cases of MPNST arising from the parapharyngeal space (PPS) in patients without neurofibromatosis have been reported. We report imaging techniques in a patient with MPNST in the PPS, who had neither a family history nor sign of NF1. Computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed for a correct therapeutic planning. CT and MRI findings were correlated with hystopathological diagnosis.

恶性外周神经鞘瘤（MPNST）在普通人群中极为罕见，在1型神经纤维瘤病（NF1）患者中更为常见。文献报道了5例无神经纤维瘤病的患者发生于咽旁间隙（PPS）的MPNST。我们报告了1例发生于PPS的MPNST患者的影像学检查，该患者既无家族史也无NF1体征。进行了计算机断层扫描（CT）和磁共振成像（MRI）以制定正确的治疗方案。CT和MRI表现与组织病理学诊断相关。