Catena C, Conti D
ENEA, Laboratorio di Dosimetria e Biofisica, CRE Casaccia, Roma.
Boll Soc Ital Biol Sper. 1990 May;66(5):413-8.
The effects of UV light or X rays in cultured Chinese hamster cells have been initially analyzed in terms of cell growth and colony survival. On the basis of these preliminary observations the induction of micronuclei has been studied on the same in vitro system. The increase in micronuclei yield appears to be dose-dependent, but also to vary according to the protocol used for micronuclei preparation. In general, the results confirm the hypothesis that micronucleus production is a dynamic phenomenon.
紫外线或X射线对培养的中国仓鼠细胞的影响最初是根据细胞生长和集落存活情况进行分析的。基于这些初步观察结果,在同一体外系统中对微核的诱导情况进行了研究。微核产量的增加似乎呈剂量依赖性,但也会因微核制备所用的方案而异。总体而言,结果证实了微核产生是一种动态现象这一假设。