抗体导向酶前药疗法 - Suppr | 超能文献

Antibody-directed enzyme prodrug therapy.

作者信息

Connors T A

机构信息

MRC Toxicology Unit, Medical Research Council Laboratories, Carshalton,Surrey, UK.

出版信息

Cancer Cells. 1990 Feb;2(2):56-7.

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Antibody-directed enzyme prodrug therapy.抗体导向酶前药疗法

Cancer Cells. 1990 Feb;2(2):56-7.

2

The choice of prodrugs for gene directed enzyme prodrug therapy of cancer.用于癌症基因导向酶前药疗法的前体药物的选择。

Gene Ther. 1995 Dec;2(10):702-9.

3

Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates.单克隆抗体 - 酶偶联物对抗癌前药的选择性激活。

Methods Find Exp Clin Pharmacol. 1994 Sep;16(7):505-12.

4

Tumor targeting: activation of prodrugs by enzyme-monoclonal antibody conjugates.肿瘤靶向：酶-单克隆抗体偶联物对前药的激活作用。

Trends Biotechnol. 1994 Jun;12(6):234-9. doi: 10.1016/0167-7799(94)90122-8.

5

Prodrugs in cancer chemotherapy.癌症化疗中的前体药物。

Stem Cells. 1995 Sep;13(5):501-11. doi: 10.1002/stem.5530130507.

6

Advances in antibody-directed enzyme prodrug therapy.抗体导向酶前药疗法的进展。

Curr Opin Investig Drugs. 2005 Jun;6(6):611-5.

7

Strategies for enzyme/prodrug cancer therapy.酶/前药癌症治疗策略。

Clin Cancer Res. 2001 Nov;7(11):3314-24.

8

[Targeting of antitumor drugs with monoclonal antibodies].[用单克隆抗体靶向抗肿瘤药物]

Bull Cancer. 2000 Nov;87(11):829-38.

9

Enzyme-catalyzed activation of anticancer prodrugs.酶催化的抗癌前药激活

Pharmacol Rev. 2004 Mar;56(1):53-102. doi: 10.1124/pr.56.1.3.

10

A phase I study of single administration of antibody-directed enzyme prodrug therapy with the recombinant anti-carcinoembryonic antigen antibody-enzyme fusion protein MFECP1 and a bis-iodo phenol mustard prodrug.一项关于单次给予抗体导向酶前药疗法的I期研究，该疗法使用重组抗癌胚抗原抗体-酶融合蛋白MFECP1和双碘苯酚氮芥前药。

Clin Cancer Res. 2006 Nov 1;12(21):6509-16. doi: 10.1158/1078-0432.CCR-06-0769.

引用本文的文献

1

Applications of monoclonal antibodies in the investigation, diagnosis, and treatment of retinoblastoma.单克隆抗体在视网膜母细胞瘤研究、诊断及治疗中的应用

Br J Ophthalmol. 1993 Dec;77(12):805-12. doi: 10.1136/bjo.77.12.805.

2

Selectivity and potency; are we doing the right things to find anti-cancer agents with these properties?选择性和效力；我们是否在做正确的事情来寻找具有这些特性的抗癌药物？

Br J Cancer. 1992 Feb;65(2):143-4. doi: 10.1038/bjc.1992.30.