• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

突破癌症疼痛的治疗：滴定还是比例？

Treatment of breakthrough cancer pain: to titrate or to proportionate?

机构信息

Department of Anesthesiology, Antwerp University Hospital (UZA) , Edegem , Belgium.

出版信息

Curr Med Res Opin. 2013 Nov;29(11):1523-6. doi: 10.1185/03007995.2013.837816. Epub 2013 Sep 5.

DOI:10.1185/03007995.2013.837816
PMID:23971682
Abstract

Breakthrough cancer pain can be treated effectively by rapid-onset opioids, such as sublingual fentanyl. However, it remained unclear how the optimal dose of sublingual fentanyl should be determined. Dosing proportional to basic opioid regimen is now proposed as an alternative to dose titration.

摘要

突破性癌症疼痛可以通过快速起效的阿片类药物（如舌下芬太尼）有效治疗。然而，目前尚不清楚应该如何确定舌下芬太尼的最佳剂量。现在建议根据基本阿片类药物方案的剂量比例进行给药，作为滴定剂量的替代方案。

相似文献

1
Treatment of breakthrough cancer pain: to titrate or to proportionate?突破癌症疼痛的治疗：滴定还是比例？
Curr Med Res Opin. 2013 Nov;29(11):1523-6. doi: 10.1185/03007995.2013.837816. Epub 2013 Sep 5.
2
A randomized, placebo-controlled study of a new sublingual formulation of fentanyl citrate (fentanyl ethypharm) for breakthrough pain in opioid-treated patients with cancer.一项关于新型枸橼酸芬太尼舌下制剂（芬太尼乙基制药）用于阿片类药物治疗的癌症患者爆发性疼痛的随机、安慰剂对照研究。
Clin Ther. 2014 Mar 1;36(3):357-67. doi: 10.1016/j.clinthera.2014.01.006. Epub 2014 Feb 5.
3
A randomized, placebo-controlled study of a new sublingual formulation of fentanyl citrate (fentanyl ethypharm) for breakthrough pain in opioid-treated patients with cancer.
Clin Ther. 2014 Nov 1;36(11):1704. doi: 10.1016/j.clinthera.2014.06.023. Epub 2014 Jul 19.
4
Intranasal fentanyl versus fentanyl pectin nasal spray for the management of breakthrough cancer pain in doses proportional to basal opioid regimen.鼻内给予芬太尼与芬太尼果胶鼻喷雾剂用于按基础阿片类药物治疗方案的比例剂量管理爆发性癌痛。
J Pain. 2014 Jun;15(6):602-7. doi: 10.1016/j.jpain.2014.02.002. Epub 2014 Feb 19.
5
The use of sublingual fentanyl for breakthrough pain by using doses proportional to opioid basal regimen.舌下芬太尼用于爆发性疼痛，剂量与阿片类药物基础方案成比例。
Curr Med Res Opin. 2013 Nov;29(11):1527-32. doi: 10.1185/03007995.2013.826640. Epub 2013 Aug 19.
6
The use of rapid onset fentanyl in children and young people for breakthrough cancer pain.速发性芬太尼在儿童和青少年中用于治疗癌症突破性疼痛。
Scand J Pain. 2017 Oct;17:256-259. doi: 10.1016/j.sjpain.2017.07.010. Epub 2017 Aug 10.
7
Lack of correlation between the effective dose of fentanyl sublingual spray for breakthrough cancer pain and the around-the-clock opioid dose.芬太尼舌下喷雾剂用于治疗爆发性癌痛的有效剂量与阿片类药物全天候剂量之间缺乏相关性。
J Opioid Manag. 2014 Jul-Aug;10(4):247-54. doi: 10.5055/jom.2014.0212.
8
Transmucosal Immediate-Release Fentanyl for Breakthrough Cancer Pain: Opportunities and Challenges for Use in Palliative Care.经黏膜即释芬太尼用于癌症突破性疼痛：姑息治疗中的应用机遇与挑战
J Pain Palliat Care Pharmacother. 2015 Sep;29(3):247-60. doi: 10.3109/15360288.2015.1063560. Epub 2015 Sep 14.
9
Dosing fentanyl buccal tablet for breakthrough cancer pain: dose titration versus proportional doses.颊用芬太尼片治疗爆发性癌痛的剂量：滴定剂量与比例剂量。
Curr Med Res Opin. 2012 Jun;28(6):963-8. doi: 10.1185/03007995.2012.683112. Epub 2012 May 22.
10
Fentanyl sublingual spray for breakthrough cancer pain in patients receiving transdermal fentanyl.芬太尼舌下喷雾剂用于接受透皮芬太尼治疗的癌症患者爆发性疼痛。
Pain Manag. 2016 Oct;6(5):427-34. doi: 10.2217/pmt-2015-0009. Epub 2016 Mar 29.

引用本文的文献

1
Once again... breakthrough cancer pain: an updated overview.再一次……突破性癌痛：最新概述。
J Anesth Analg Crit Care. 2023 Jul 21;3(1):23. doi: 10.1186/s44158-023-00101-x.
2
Rapid-Onset Opioids for Management of Breakthrough Cancer Pain: Considerations for Daily Practice.用于管理癌症突发疼痛的快速起效阿片类药物：日常实践中的考量
Front Pain Res (Lausanne). 2022 May 26;3:893530. doi: 10.3389/fpain.2022.893530. eCollection 2022.
3
The use of low doses of a sublingual fentanyl formulation for breakthrough pain in patients receiving low doses of opioids.
在接受低剂量阿片类药物治疗的患者中，使用低剂量舌下含服芬太尼制剂治疗爆发性疼痛。
Support Care Cancer. 2017 Feb;25(2):645-649. doi: 10.1007/s00520-016-3457-y. Epub 2016 Oct 15.
4
What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion.诊断和治疗突破性癌痛（BTcP）时的注意事项：专家意见
Drugs. 2016 Mar;76(3):315-30. doi: 10.1007/s40265-015-0519-2.