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孕期慢性阿片类药物使用:对母体和胎儿的影响。

Chronic opioid use during pregnancy: maternal and fetal implications.

机构信息

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA.

出版信息

Clin Perinatol. 2013 Sep;40(3):337-50. doi: 10.1016/j.clp.2013.05.015. Epub 2013 Jul 4.

Abstract

Current trends in the United States suggest that chronic narcotic use has increased in reproductive aged women over the past 10 years. Regular exposure to such substances during pregnancy has maternal and fetal implications. Appropriate prenatal care is critical to optimizing outcomes. Management options for narcotic dependence should be patient-specific and may include discontinuation of narcotics with careful observation, limitation of prescription dispensing, or substitution therapy with methadone or buprenorphine. A multidisciplinary, collaborative approach is highly recommended. This review discusses usage of narcotic medications, associated maternal and fetal risks, and management strategies for the antepartum, intrapartum, and postpartum periods.

摘要

美国当前的趋势表明,在过去 10 年中,生育年龄的女性慢性使用麻醉品的情况有所增加。怀孕期间经常接触这些物质会对母婴产生影响。适当的产前护理对于优化母婴结局至关重要。针对麻醉品依赖的处理方案应根据患者的具体情况而定,可能包括谨慎观察下停止使用麻醉品、限制开具处方、或用美沙酮或丁丙诺啡替代治疗。强烈建议采用多学科协作的方法。本文讨论了麻醉药物的使用、相关的母婴风险,以及产前、产时和产后管理策略。

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