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婴幼儿主动脉弓重建期间急性肾损伤和肾局部氧饱和度。

Acute kidney injury and renal regional oxygen saturation during aortic arch reconstruction in infants.

机构信息

Department of Anesthesiology and Pain Medicine, Jeju National University School of Medicine, Jeju, Korea.

出版信息

J Cardiothorac Vasc Anesth. 2013 Dec;27(6):1153-7. doi: 10.1053/j.jvca.2013.03.035. Epub 2013 Aug 20.

DOI:10.1053/j.jvca.2013.03.035
PMID:23972985
Abstract

OBJECTIVE

Acute kidney injury is a serious postoperative complication following cardiac surgery. The aortic arch repair technique using antegrade selective cerebral perfusion has been used, but it is unclear whether subdiaphragmatic organs such as the kidneys are perfused adequately. The authors compared intraoperative renal regional oxygen saturation using near-infrared spectroscopy between infants with and without postoperative acute kidney injury after undergoing aortic arch reconstruction.

DESIGN

Retrospective medical records review.

SETTING

University medical center.

PARTICIPANTS

Elective cardiac surgical infants.

INTERVENTIONS

The author reviewed the perioperative clinical records of infants who underwent aortic arch reconstruction surgery using antegrade selective cerebral perfusion. During the operation, prestenotic (right radial or right brachial artery) and poststenotic (femoral or umbilical artery) invasive arterial blood pressure and cerebral and renal regional oxygen saturation were monitored continuously. Development of acute kidney injury within 72 hours of surgery was investigated.

RESULTS

A total of 47 patients were enrolled in this study. Postoperative acute kidney injury occurred in 19 patients (40.4%). Intraoperative renal regional oxygen saturation was similar between patients with and without acute kidney injury. Intraoperative prestenotic and poststenotic mean arterial blood pressure and cerebral regional oxygen saturation also were similar between the 2 groups.

CONCLUSIONS

The intraoperative renal tissue oxygen saturation was not different between the groups with or without postoperative acute kidney injury in infants who underwent aortic arch repair using antegrade selective cerebral perfusion.

摘要

目的

心脏手术后急性肾损伤是一种严重的术后并发症。目前已经使用了升主动脉弓修复技术中的顺行性选择性脑灌注,但尚不清楚肾脏等膈下器官是否得到充分灌注。作者比较了行升主动脉弓重建术的婴儿中术后发生急性肾损伤与未发生急性肾损伤者的术中肾脏局部氧饱和度。

设计

回顾性病历审查。

地点

大学医疗中心。

参与者

择期心脏手术婴儿。

干预措施

作者复习了接受顺行性选择性脑灌注升主动脉弓重建术的婴儿围手术期临床病历。手术期间,连续监测术前(右桡动脉或右肱动脉)和术后(股动脉或脐动脉)有创动脉血压和脑及肾局部氧饱和度。研究术后 72 小时内急性肾损伤的发生情况。

结果

本研究共纳入 47 例患者。19 例(40.4%)患者术后发生急性肾损伤。急性肾损伤组与无急性肾损伤组患者术中肾脏局部氧饱和度相似。两组患者术中术前和术后平均动脉血压和脑局部氧饱和度也相似。

结论

在接受顺行性选择性脑灌注升主动脉弓修复的婴儿中,术后发生急性肾损伤组与未发生急性肾损伤组患者术中肾脏组织氧饱和度无差异。

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