Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
Immunity. 2013 Aug 22;39(2):208-10. doi: 10.1016/j.immuni.2013.08.015.
Sex bias in susceptibility to autoimmune diseases is evident but poorly characterized. Yurkovetskiy et al. (2013) report that host testosterone mediates changes in the microbiome to confer protection to adult male NOD mice from type 1 diabetes.
自身免疫性疾病易感性的性别偏倚是显而易见的,但特征描述不足。Yurkovetskiy 等人(2013 年)报告称,宿主睾丸酮介导了微生物组的变化,从而使成年雄性 NOD 小鼠免受 1 型糖尿病的影响。