黎巴嫩北部产 Panton-Valentine 白细胞毒素的金黄色葡萄球菌鼻腔携带。
Panton-Valentine leukocidin producing Staphylococcus aureus nasal carriage, in North-Lebanon.
机构信息
Laboratoire de microbiologie santé et environnement, centre AZM pour la recherche en biotechnologies et ses applications, école doctorale des sciences et de technologie, université Libanaise, Tripoli, Lebanon.
出版信息
Med Mal Infect. 2013 Sep;43(9):386-90. doi: 10.1016/j.medmal.2013.07.005. Epub 2013 Aug 20.
OBJECTIVES
We investigated the prevalence and the risk factors of nasal carriage of Staphylococcus aureus carrying Panton-Valentine leukocidin genes [Sa PVL(+)] in pupils.
STUDY POPULATION AND METHODS
Two hundred and fifty-seven pupils were screened by nasal swabbing. The detection of 16S rRNA, mecA and luk-PV genes was performed by PCR and the risk factors were assessed with the statistical analysis of a questionnaire.
RESULTS
Thirty-one percent of pupils were colonized, with 16.4% of isolates carrying the luk-PV gene and 8.8% the mecA gene. Children aged 7years or more and living in a boarding school were the factors promoting nasal carriage 60% of children who presented with an abscess in the previous year were carriers of luk-PV gene Sa.
CONCLUSION
The study revealed a high prevalence of luk-PV gene among methicillin-susceptible strains and a statistically significant correlation between the presence of this gene and presenting with an abscess.
目的
我们调查了携带杀白细胞素基因 [Sa PVL(+)] 的金黄色葡萄球菌在小学生中的流行情况和风险因素。
研究人群和方法
通过鼻拭子对 257 名小学生进行筛查。通过 PCR 检测 16S rRNA、mecA 和 luk-PV 基因，并通过问卷调查评估风险因素。
结果
31%的小学生定植，16.4%的分离株携带 luk-PV 基因，8.8%的分离株携带 mecA 基因。7 岁及以上且住校的儿童是促进鼻定植的因素，去年有脓肿的儿童中有 60%携带 luk-PV 基因 Sa。
结论
本研究显示了耐甲氧西林金黄色葡萄球菌中 luk-PV 基因的高流行率，以及该基因的存在与脓肿的发生之间存在统计学显著相关性。
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