Emergency Department, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
PLoS One. 2013 Aug 20;8(8):e71801. doi: 10.1371/journal.pone.0071801. eCollection 2013.
The risk of acute pancreatitis in patients on long-term peritoneal dialysis is higher as compared to the general population. However, the relationship between long-term hemodialysis and acute pancreatitis has never been established.
We investigated the incidence of acute pancreatitis among patients on long-term hemodialysis in Taiwan to evaluate if there is a higher risk of acute pancreatitis in comparison to the general population.
We utilized a National Health Insurance (NHI) claims data sample containing one million beneficiaries. We followed all adult beneficiaries from January 1, 2007 until December 31, 2010 to see if they had been hospitalized for acute pancreatitis during this period. We further identified patients on chronic hemodialysis and compared their risk of acute pancreatitis with the general population.
This study included 2603 patients with long-term hemodialysis and 773,140 patients without hemodialysis. After controlling for age, gender, Charlson Comorbidity Index Score, geographic region, socioeconomic status and urbanization level, the adjusted hazard ratio was 3.44 (95% Confidence interval, 2.5-4.7).
The risk of acute pancreatitis in patients on long-term hemodialysis is significantly higher in comparison to the general population.
与普通人群相比，长期进行腹膜透析的患者发生急性胰腺炎的风险更高。然而，长期血液透析与急性胰腺炎之间的关系尚未确定。
我们调查了在台湾进行长期血液透析的患者中急性胰腺炎的发病率，以评估与普通人群相比，他们发生急性胰腺炎的风险是否更高。
我们利用了包含 100 万受益人的全民健康保险（NHI）理赔数据样本。我们从 2007 年 1 月 1 日至 2010 年 12 月 31 日对所有成年受益人的情况进行了随访，以了解在此期间他们是否因急性胰腺炎住院。我们进一步确定了慢性血液透析患者，并将他们发生急性胰腺炎的风险与普通人群进行了比较。
本研究纳入了 2603 例长期血液透析患者和 773140 例未接受血液透析的患者。在控制年龄、性别、Charlson 合并症指数评分、地理区域、社会经济状况和城市化水平后，调整后的危险比为 3.44（95%置信区间，2.5-4.7）。
与普通人群相比，长期血液透析患者发生急性胰腺炎的风险显著更高。
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