Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, SC 29401, USA.
Int J Psychiatry Med. 2013;45(2):111-24. doi: 10.2190/PM.45.2.b.
Exposure-based therapy is an effective treatment for PTSD, including combat-related PTSD. However, questions remain within PTSD treatment literature and among front-line clinicians about the appropriateness of exposure-based therapies for older adults. The current study examined the effectiveness of Prolonged Exposure (PE) in reducing PTSD and depression symptoms in a sample of 65 Veterans age 60 and older who were diagnosed with PTSD via structured clinical interview. In addition to within-subject repeated measure analyses, the entire intent to treat sample was compared to treatment completers. Within group d-type effect sizes across both groups were large (1.13-1.90) and the retention rate was high (85%). Importantly, no adverse medical or psychiatric events were reported over the course of the study. Results are discussed and limitations, along with future directions, are presented.
暴露疗法是一种治疗创伤后应激障碍（PTSD）的有效方法，包括与战斗相关的 PTSD。然而，在 PTSD 治疗文献和一线临床医生中，仍存在关于暴露疗法是否适合老年患者的问题。本研究通过结构临床访谈，对 65 名年龄在 60 岁及以上的 PTSD 退伍军人进行了延长暴露（PE）治疗，以评估其对 PTSD 和抑郁症状的疗效。除了对被试内重复测量的分析外，还将整个意向治疗样本与治疗完成者进行了比较。两组内的 d 型效应量均较大（1.13-1.90），且保留率较高（85%）。重要的是，在研究过程中没有报告任何不良的医疗或精神事件。结果进行了讨论，并提出了研究的局限性和未来方向。
