University of Houston College of Pharmacy, 1441 Moursund St, Houston, TX 77030, USA.
Expert Rev Anti Infect Ther. 2013 Aug;11(8):831-7. doi: 10.1586/14787210.2013.816463.
Infections caused by Pseudomonas aeruginosa can be difficult to treat and require a coordinated approach for their management. This involves quickly controlling the source of infection, establishing a correct etiologic diagnosis and administering appropriate empiric antimicrobial therapy. Once antimicrobial therapy has been initiated and susceptibilities are available, therapy should be tailored with optimized antibiotic doses for an appropriate duration in order to sufficiently treat the infection and minimize resistance emergence.
铜绿假单胞菌引起的感染难以治疗,需要采取综合措施进行管理。这包括迅速控制感染源、明确病因诊断和给予适当的经验性抗菌治疗。一旦开始抗菌治疗且药敏结果可用,应根据感染情况优化抗生素剂量并调整用药时间,以充分治疗感染并最大程度减少耐药性的产生。