Montebugnoli L, Pelliccioni G A, Borghi C
Università degli Studi di Bologna.
Dent Cadmos. 1990 May 31;58(9):62-71.
In this study, the effects of epinephrine in the local anesthesia were valued. No significant differences were revealed to cardiovascular response when a group of patients under generic stress were given an anesthetic without epinephrine and a second group of patients underwent an anesthetic with epinephrine. In patients in which epinephrine was injected, a significant fall in diastolic blood pressure was recorded two minutes after the injection and it remained as such for ten minutes. The cardiovascular response during dental extraction has a significant result dissimilar in the two groups of patients. No significant correlation was revealed between the blood pressure and the heart rate in basic conditions and the same parameters during an extraction. There exists a significant correlation between pressure response during generic stress and pressure response during an extraction. These findings suggest that cardiovascular response during dental stress is not in relation with the use of epinephrine with an anesthetic, but rather depends on each individual reaction.
