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手术与非手术治疗持续性主动脉内漏导致的慢性弥散性血管内凝血

Operative and nonoperative management of chronic disseminated intravascular coagulation due to persistent aortic endoleak.

机构信息

Division of Vascular Surgery, Mayo Clinic, Rochester, Minn.

Division of Vascular Surgery, Mayo Clinic, Rochester, Minn.

出版信息

J Vasc Surg. 2014 May;59(5):1426-9. doi: 10.1016/j.jvs.2013.05.097. Epub 2013 Aug 24.

Abstract

Disseminated intravascular coagulation (DIC) due to endoleak is a rare complication following endovascular aneurysm repair. Two of the four previously reported cases occurred in patients with cirrhosis. We describe three patients with normal liver function who developed DIC due to delayed high-flow (type Ia or III) endoleaks. Two patients underwent successful surgical repair, and the third was managed medically. All three patients had chronic thrombocytopenia prior to developing an endoleak as did the four reported cases in the literature. We propose that thrombocytopenia, like cirrhosis, be considered a risk factor for DIC due to endoleaks in patients undergoing endovascular aneurysm repair.

摘要

弥漫性血管内凝血(DIC)是血管内治疗后罕见的并发症。在之前报道的四例病例中,有两例发生在肝硬化患者中。我们描述了三例肝功能正常的患者,他们由于延迟的高流量(Ia 型或 III 型)内漏而发生 DIC。两名患者成功接受了手术修复,第三名患者接受了药物治疗。在发生内漏之前,所有三名患者均有慢性血小板减少症,文献报道的四例病例也是如此。我们建议,血小板减少症与肝硬化一样,应被视为血管内治疗后发生内漏导致 DIC 的危险因素。

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