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简要报告:新发 2 型糖尿病成年患者的抑郁和自杀未遂史。

Brief report: depression and history of suicide attempts in adults with new-onset Type 2 Diabetes.

机构信息

Department of Psychiatry, University of Texas at Southwestern Medical Center, Dallas, TX, United States; Division of Endocrinology, University of Texas at Southwestern Medical Center, Dallas, TX, United States.

出版信息

Psychoneuroendocrinology. 2013 Nov;38(11):2810-4. doi: 10.1016/j.psyneuen.2013.06.013. Epub 2013 Aug 24.

Abstract

AIM

To assess past suicide attempts in a cohort of adults with Type 2 Diabetes diagnosed within the prior 24 months.

METHODS

Outpatients were recruited from diabetes education classes or diabetes shared medical appointment. Participants aged 18 or over with a self-reported diagnosis of Type 2 Diabetes (T2DM) in the prior 24 months completed questionnaires about medical (including diabetes), psychiatric, and social history. Participants also completed two screening questionnaires for depression: Patient Health Questionnaire 9 and the Questionnaire Inventory for Depressive Symptoms-Self Report. Those who screened positive for depression had confirmatory testing with a clinician administered Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) checklist.

RESULTS

In this convenience sample of 145 patients with Type 2 Diabetes, 9.7% of patients had history of a suicide attempt and 38.2% met diagnosis for major depressive disorder (MDD). Patients with MDD were more likely to have a history of suicide attempts than those without MDD (p=0.0002). Of the patients with prior suicide attempts, 50% screened positive for MDD at the time of the survey.

CONCLUSION

In patients with newly-diagnosed Type 2 Diabetes the rate of past suicide attempts was nearly 10%, which is twice the rate seen in the general population. The rate of past suicide attempts in currently depressed patients with diabetes is 21.8%. These findings suggest the need for monitoring patients with diabetes and depression for future suicide risk.

摘要

目的

评估在过去 24 个月内被诊断为 2 型糖尿病的成年人队列中过去的自杀尝试情况。

方法

从糖尿病教育课程或糖尿病共享医疗预约中招募门诊患者。年龄在 18 岁及以上、自我报告在过去 24 个月内被诊断为 2 型糖尿病(T2DM)的患者完成了关于医疗(包括糖尿病)、精神和社会史的问卷。患者还完成了两个抑郁筛查问卷:患者健康问卷 9 项和抑郁症状问卷自我报告。那些在抑郁筛查中呈阳性的患者通过临床医生管理的精神障碍诊断和统计手册(DSM-IV)检查表进行了确认性测试。

结果

在这项方便的 145 名 2 型糖尿病患者的样本中,有 9.7%的患者有自杀企图史,38.2%的患者符合重性抑郁障碍(MDD)的诊断。有 MDD 的患者比没有 MDD 的患者更有可能有自杀企图史(p=0.0002)。在有既往自杀企图的患者中,有 50%在调查时对 MDD 筛查呈阳性。

结论

在新诊断为 2 型糖尿病的患者中,过去自杀企图的发生率接近 10%,是一般人群的两倍。目前患有糖尿病和抑郁的患者中过去自杀企图的发生率为 21.8%。这些发现表明需要监测患有糖尿病和抑郁的患者未来的自杀风险。

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