膀胱癌：马兜铃酸——人类已知的最具致癌性的物质之一。 - Suppr

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Bladder cancer: aristolochic acid--one of the most potent carcinogens known to man.

作者信息

Clyne Melanie

出版信息

Nat Rev Urol. 2013 Oct;10(10):552. doi: 10.1038/nrurol.2013.186. Epub 2013 Aug 27.

DOI:10.1038/nrurol.2013.186

PMID:23979661

Abstract

摘要

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引用本文的文献

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Sci Rep. 2015 Dec 1;5:17646. doi: 10.1038/srep17646.

Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.福尔马林固定石蜡包埋肿瘤的低覆盖度外显子组测序筛查揭示了接触致癌马兜铃酸的证据。

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本文引用的文献

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.全外显子测序揭示的马兜铃酸暴露的突变特征。

Sci Transl Med. 2013 Aug 7;5(197):197ra102. doi: 10.1126/scitranslmed.3006200.

Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.马兜铃酸的全基因组突变特征及其作为筛选工具的应用。

Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086.

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