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Bladder cancer: aristolochic acid--one of the most potent carcinogens known to man.

作者信息

Clyne Melanie

出版信息

Nat Rev Urol. 2013 Oct;10(10):552. doi: 10.1038/nrurol.2013.186. Epub 2013 Aug 27.

DOI:10.1038/nrurol.2013.186
PMID:23979661
Abstract
摘要

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Bladder cancer: aristolochic acid--one of the most potent carcinogens known to man.膀胱癌：马兜铃酸——人类已知的最具致癌性的物质之一。
Nat Rev Urol. 2013 Oct;10(10):552. doi: 10.1038/nrurol.2013.186. Epub 2013 Aug 27.
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Genomics traces carcinogen fingerprints.基因组学追踪致癌物指纹。
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Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.马兜铃酸的全基因组突变特征及其作为筛选工具的应用。
Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086.
4
Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.全外显子测序揭示的马兜铃酸暴露的突变特征。
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Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid.分析 TP53 突变谱揭示了强效环境致癌物马兜铃酸的指纹图谱。
Mutat Res. 2013 Jul-Sep;753(1):41-49. doi: 10.1016/j.mrrev.2013.02.003. Epub 2013 Feb 17.
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Mutational Processes in Hepatocellular Carcinoma: The Story of Aristolochic Acid.肝细胞癌中的突变过程：马兜铃酸的故事。
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Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.台湾马兜铃酸相关性上尿路上皮癌：临床特征与结局。
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Late onset of bladder urothelial carcinoma after kidney transplantation for end-stage aristolochic acid nephropathy: a case series with 15-year follow-up.终末期马兜铃酸肾病肾移植术后膀胱尿路上皮癌的迟发：一项长达15年随访的病例系列研究
Am J Kidney Dis. 2008 Mar;51(3):471-7. doi: 10.1053/j.ajkd.2007.11.015.
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Aristolochic acids.马兜铃酸
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Population-based case-control study of Chinese herbal products containing aristolochic acid and urinary tract cancer risk.基于人群的中药含马兜铃酸与尿路癌风险的病例对照研究。
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引用本文的文献

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Ensemble forecasting of a continuously decreasing trend in bladder cancer incidence in Taiwan.台湾膀胱癌发病率持续下降趋势的综合预测。
Sci Rep. 2021 Apr 16;11(1):8373. doi: 10.1038/s41598-021-87770-2.
2
Reduction in the Incidence of Urological Cancers after the Ban on Chinese Herbal Products Containing Aristolochic Acid: An Interrupted Time-Series Analysis.含马兜铃酸的中草药制品禁令后泌尿系统癌症发病率的降低：一项中断时间序列分析。
Sci Rep. 2019 Dec 27;9(1):19860. doi: 10.1038/s41598-019-56394-y.
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Development and validation of a nomogram for urothelial cancer in patients with chronic kidney disease.

本文引用的文献

1
Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.全外显子测序揭示的马兜铃酸暴露的突变特征。
Sci Transl Med. 2013 Aug 7;5(197):197ra102. doi: 10.1126/scitranslmed.3006200.
2
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.马兜铃酸的全基因组突变特征及其作为筛选工具的应用。
Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086.
构建并验证用于慢性肾脏病患者尿路上皮癌的列线图
Sci Rep. 2019 Mar 5;9(1):3473. doi: 10.1038/s41598-019-40276-4.
4
Genetic Variations of Melatonin Receptor Type 1A are Associated with the Clinicopathologic Development of Urothelial Cell Carcinoma.褪黑素受体 1A 的遗传变异与尿路上皮细胞癌的临床病理发展相关。
Int J Med Sci. 2017 Sep 4;14(11):1130-1135. doi: 10.7150/ijms.20629. eCollection 2017.
5
Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms.马兜铃酸系统效应的预测与表征：一种针对治疗和毒理机制的新型联合网络分析
Sci Rep. 2015 Dec 1;5:17646. doi: 10.1038/srep17646.
6
Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.福尔马林固定石蜡包埋肿瘤的低覆盖度外显子组测序筛查揭示了接触致癌马兜铃酸的证据。
Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1873-81. doi: 10.1158/1055-9965.EPI-15-0553. Epub 2015 Sep 17.