Kasturba Medical College, Manipal, India.
J Ultrasound Med. 2013 Sep;32(9):1539-46. doi: 10.7863/ultra.32.9.1539.
To analyze qualitative and quantitative parameters of lung tumors by color Doppler sonography, determine the role of color Doppler sonography in predicting chest wall invasion by lung tumors using spectral waveform analysis, and compare color Doppler sonography and computed tomography (CT) for predicting chest wall invasion by lung tumors.
Between March and September 2007, 55 patients with pleuropulmonary lesions on chest radiography were assessed by grayscale and color Doppler sonography for chest wall invasion. Four patients were excluded from the study because of poor acoustic windows. Quantitative and qualitative sonographic examinations of the lesions were performed using grayscale and color Doppler imaging. The correlation between the color Doppler and CT findings was determined, and the final outcomes were correlated with the histopathologic findings.
Of a total of 51 lesions, 32 were malignant. Vascularity was present on color Doppler sonography in 28 lesions, and chest wall invasion was documented in 22 cases. Computed tomography was performed in 24 of 28 evaluable malignant lesions, and the findings were correlated with the color Doppler findings for chest wall invasion. Of the 24 patients who underwent CT, 19 showed chest wall invasion. The correlation between the color Doppler and CT findings revealed that color Doppler sonography had sensitivity of 95.6% and specificity of 100% for assessing chest wall invasion, whereas CT had sensitivity of 85.7% and specificity of 66.7%.
Combined qualitative and quantitative color Doppler sonography can predict chest wall invasion by lung tumors with better sensitivity and specificity than CT. Although surgery is the reference standard, color Doppler sonography is a readily available, affordable, and noninvasive in vivo diagnostic imaging modality that is complementary to CT and magnetic resonance imaging for lung cancer staging.
通过彩色多谱勒超声分析肺部肿瘤的定性和定量参数，利用频谱波形分析确定彩色多谱勒超声在预测肺部肿瘤胸壁侵犯中的作用，并比较彩色多谱勒超声和计算机断层扫描（CT）在预测肺部肿瘤胸壁侵犯中的作用。
2007 年 3 月至 9 月期间，对 55 例胸部 X 线摄影有胸膜肺病变的患者进行了灰阶和彩色多谱勒超声检查，以评估胸壁侵犯情况。由于声窗不佳，有 4 例患者被排除在研究之外。使用灰阶和彩色多普勒成像对病变进行了定性和定量超声检查。对彩色多谱勒和 CT 检查结果进行了相关性分析，并将最终结果与组织病理学发现进行了相关性分析。
共有 51 个病灶，其中 32 个为恶性。28 个病灶在彩色多谱勒超声上显示有血流，其中 22 个病例有胸壁侵犯。28 个可评估的恶性病变中有 24 个进行了 CT 检查，其结果与彩色多谱勒对胸壁侵犯的检查结果相关。在这 24 例接受 CT 检查的患者中，有 19 例显示有胸壁侵犯。彩色多谱勒和 CT 检查结果的相关性分析表明，彩色多谱勒超声对胸壁侵犯的评估具有 95.6%的敏感性和 100%的特异性，而 CT 检查的敏感性为 85.7%，特异性为 66.7%。
定性和定量彩色多谱勒超声联合检查可预测肺部肿瘤的胸壁侵犯，其敏感性和特异性均优于 CT。尽管手术是参考标准，但彩色多谱勒超声是一种易于获得、经济实惠、非侵入性的体内诊断成像方式，可与 CT 和磁共振成像互补，用于肺癌分期。
