Chawla Y, Dilawari J B
Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Clin Gastroenterol. 1990 Aug;12(4):378-80.
To compare the efficacy of 3% sodium tetradecyl sulphate (STS) with absolute alcohol (AA), we randomly assigned 52 patients with portal hypertension to one of the two sclerosants. Obliteration of esophageal varices was seen with an almost similar number of sessions (5.2 +/- 1.8 with STS and 4.7 +/- 1.5 with AA). Esophageal ulceration was more common with STS, while severe retrosternal pain was seen only with absolute alcohol. However, there was no statistical significance to these differences. The study suggests that absolute alcohol might be a suitable alternative to STS.
为比较3%十四烷基硫酸钠（STS）与无水乙醇（AA）的疗效，我们将52例门静脉高压患者随机分为两组，分别接受两种硬化剂治疗。两组消除食管静脉曲张所需的治疗次数相近（STS组为5.2±1.8次，AA组为4.7±1.5次）。食管溃疡在STS组更为常见，而严重胸骨后疼痛仅在无水乙醇组出现。然而，这些差异无统计学意义。该研究表明，无水乙醇可能是STS的合适替代物。
