Ferrante Kimberly L, Kim Hae-Young, Brubaker Linda, Wai Cliff Y, Norton Peggy A, Kraus Stephen R, Shepherd Jonathan, Sirls Larry T, Nager Charles W
University of California, San Diego, La Jolla, California.
Neurourol Urodyn. 2014 Nov;33(8):1225-8. doi: 10.1002/nau.22489. Epub 2013 Aug 27.
This study examined the association between the need for a repeat voiding trial after midurethral sling (MUS) surgery and 1-year success rates.
We conducted this secondary analysis of the participants in the Urinary Incontinence Treatment Network trial of midurethral sling (TOMUS) study which compared retropubic versus transobturator MUS. A standard voiding trial was attempted on all subjects. The "repeat voiding trial" group included subjects discharged with catheterization. All others were considered "self voiding." Success rates between the groups at 1-year were compared, followed by multivariate analyses controlling for previously reported clinical predictors of success.
Most women (76%) were self-voiding, while 24% required a repeat voiding trial. The objective success rate at 1-year was 85.8% in the repeat voiding trial group and 75.3% in the self-voiding group (P = 0.01). Subjective success rate at 1-year was 61.0% in the repeat voiding trial group and 55.1% in the self-voiding group (P = 0.23). Women in the repeat voiding trial group continued to demonstrate greater objective success than the self-voiding group in multivariate analysis that controlled for previous incontinence surgery, pad weight, urethral mobility, urge score, and type of MUS (P = 0.04, OR 1.82, 95% CI 1.03-3.22).
Women who require a repeat voiding trial following MUS surgery have greater objective success at 1-year postoperatively when compared to those who are self-voiding at the time of discharge. These results may help reassure women who require catheterization after MUS surgery that their outcome is not compromised by this immediate transient post-operative result.
本研究探讨了经尿道中段吊带术(MUS)后重复排尿试验需求与1年成功率之间的关联。
我们对尿失禁治疗网络经尿道中段吊带术试验(TOMUS)研究的参与者进行了二次分析,该研究比较了耻骨后与经闭孔MUS。对所有受试者尝试进行标准排尿试验。“重复排尿试验”组包括带导尿管出院的受试者。所有其他受试者被视为“自主排尿”。比较两组1年时的成功率,随后进行多变量分析,控制先前报道的成功临床预测因素。
大多数女性(76%)自主排尿,而24%需要重复排尿试验。重复排尿试验组1年时的客观成功率为85.8%,自主排尿组为75.3%(P = 0.01)。重复排尿试验组1年时的主观成功率为61.0%,自主排尿组为55.1%(P = 0.23)。在控制了先前的尿失禁手术、护垫重量、尿道活动度、尿急评分和MUS类型的多变量分析中,重复排尿试验组的女性继续显示出比自主排尿组更高的客观成功率(P = 0.04,OR 1.82,95% CI 1.03 - 3.22)。
与出院时自主排尿的女性相比,MUS手术后需要重复排尿试验的女性术后1年的客观成功率更高。这些结果可能有助于让MUS手术后需要导尿的女性放心,她们的预后不会因这种即时的术后短暂结果而受到影响。