Trogrlić Ivo, Trogrlić Dragan, Trogrlić Zoran
DREN Ltd, Žepče, Bukovik 3, 72230 Žepčce, B & H, Bosnia & Herzegovina.
Afr J Tradit Complement Altern Med. 2011 Oct 2;9(1):67-72. doi: 10.4314/ajtcam.v9i1.10. eCollection 2012.
The study aims at demonstrating the efficiency of phytotherapy in regulation of prolactin levels in patients diagnosed with pituitary macroprolactinoma. The study made use of workup outcomes submitted by treating healthcare facilities where the patients were first diagnosed with macroprolactinomas based on diagnostic imaging (MRI and/or CT), laboratory workup, and hormone status estimation. The data in reference served as the baseline for a comparative follow-up of phytotherapeutic efficiency in terms of comparison of medical data obtained prior to phytotherapy and those submitted following herbal remedy use. The study displays the results of a five-year follow-up of macroprolactinoma patients undergoing phytotherapy. In well-responding patients, the benefit of phytotherapy in terms of prolactin level putdown can be seen 3-5 months following the phytotherapy commencement. A special attention should be paid to the favourable results obtained with patients who chose to resort to phytotherapy only. The primary outcome measure used to monitor the efficiency of the administered phytotherapy was prolactin level determined prior to, during the course of, and following phytotherapy. Implementation of phytotherapy to the effect of prolactin level regulation in patients diagnosed with macroprolactinoma, represents a completely novel therapeutic approach. The majority of the diseased resorted to phytotherapy once they were left out of any other therapeutic option offered by their treating healthcare facilities. This fact gives a substantial rise to the significance of the results presented herein and justifies the role of phytotherapy in macroprolactinoma-induced hyperprolactinaemia treatment.
本研究旨在证明植物疗法在调节垂体大泌乳素瘤患者泌乳素水平方面的有效性。该研究利用了治疗医疗机构提交的检查结果,这些患者最初是根据诊断成像(MRI和/或CT)、实验室检查和激素状态评估被诊断为大泌乳素瘤的。参考数据作为比较植物疗法疗效的基线,用于比较植物疗法之前和使用草药后获得的医学数据。该研究展示了接受植物疗法的大泌乳素瘤患者的五年随访结果。在反应良好的患者中,植物疗法开始后3至5个月,泌乳素水平下降方面的益处可见。对于仅选择采用植物疗法的患者所获得的良好结果应予以特别关注。用于监测所实施植物疗法疗效的主要指标是在植物疗法之前、过程中和之后测定的泌乳素水平。对被诊断为大泌乳素瘤的患者实施植物疗法以调节泌乳素水平,代表了一种全新的治疗方法。大多数患者在被其治疗医疗机构提供的任何其他治疗选择排除在外后,才求助于植物疗法。这一事实极大地提升了本文所呈现结果的重要性,并证明了植物疗法在大泌乳素瘤所致高泌乳素血症治疗中的作用。