Sobhy Tamer S
Faculty of Medicine, Ain Shams University, 15 Khalifa Maamoon, Heliopolis, Cairo, Egypt.
Int J Otolaryngol. 2013;2013:603493. doi: 10.1155/2013/603493. Epub 2013 Aug 4.
Background. Intranasal steroid provides an efficient nonsurgical alternative to adenoidectomy for theimprovement of adenoid nasal obstruction. Objective. To demonstrate the role of intranasal steroid in the prevention of adenoid regrowth after adenoidectomy. Methods. Prospective randomized controlled study. Two hundred children after adenoidectomy were divided into 2 groups. Group I received postoperative intranasal steroid and group II received postoperative intranasal saline spray. Both medications were administered for 12 weeks postoperatively. Patients were followed up for 1 year. Followup was done using the nasopharyngeal lateral X-rays, reporting the degree of the symptoms. Results. Significant difference between both groups after 6 months and after 1 year. The intranasal steroid group had significantly lower score after 6 months and after 1 year as regards nasal obstruction, nasal discharge, and snoring than the intranasal saline group. 2 weeks postoperatively, there was no difference between both groups as regards nasal obstruction, discharge, or snoring. As regards lateral radiographs, there was statistically significant difference between both groups 1 year but not 6 months postoperatively. Conclusion. Factors influencing the outcome of intranasal steroids therapy in the prevention of adenoid regrowth have not been identified. However, this treatment may obtain successful results in children to avoid readenoidectomy.
背景。鼻内用类固醇为改善腺样体所致鼻阻塞提供了一种有效的非手术替代腺样体切除术的方法。目的。证明鼻内用类固醇在腺样体切除术后预防腺样体再生中的作用。方法。前瞻性随机对照研究。200例腺样体切除术后的儿童被分为两组。第一组术后接受鼻内用类固醇治疗,第二组术后接受鼻内用生理盐水喷雾治疗。两种药物均在术后使用12周。对患者进行1年的随访。使用鼻咽侧位X线片进行随访,报告症状的严重程度。结果。6个月和1年后两组之间存在显著差异。在鼻阻塞、鼻分泌物和打鼾方面,鼻内用类固醇组在6个月和1年后的评分显著低于鼻内用生理盐水组。术后2周,两组在鼻阻塞、分泌物或打鼾方面无差异。关于侧位X线片,两组在术后1年有统计学显著差异,但6个月时无差异。结论。尚未确定影响鼻内用类固醇治疗预防腺样体再生效果的因素。然而,这种治疗可能在儿童中取得成功结果,以避免再次进行腺样体切除术。