McLaughlin Nancy, Kelly Daniel F, Prevedello Daniel M, Shahlaie Kiarash, Carrau Ricardo L, Kassam Amin B
Brain Tumor Center, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California.
Skull Base Rep. 2011 May;1(1):27-32. doi: 10.1055/s-0031-1275253. Epub 2011 Mar 30.
Petrous apex cholesterol granulomas (PACG) are uncommon lesions. Recurrence following transcranial or endonasal approaches to aerate the cyst occurs in up to 60% of cases. We describe the technical nuances pertinent to the endonasal endoscopic management of a recurrent symptomatic PACG and review the literature. A 19-year-old woman presented with a recurrent right abducens nerve paresis. Four months prior, she underwent an endonasal transsphenoidal surgery (TSS) for drainage of a symptomatic PACG. Current imaging documented recurrence of the right PACG. Transsphenoidal and infrapetrous approaches were performed to obtain a wider bony opening along the petrous apex and drain the cyst. A Doyle splint was inserted into the cyst's cavity and extended out into the sphenoid, maintaining patency during the healing process. Three months after surgery, the splint was removed endoscopically, allowing visualization of a patent cylindrical communication between both aerated cavities. The patient remains symptom- and recurrence-free. Endoscopic endonasal surgery must be adapted to manage recurrent PACG. A TSS may not be sufficient. An infrapetrous approach with wider bony opening, extensive removal of the cyst's anterior wall, and use of a stent are indicated for the treatment of recurrent PACG and to prevent recurrences.
岩尖胆固醇肉芽肿(PACG)是一种罕见的病变。经颅或经鼻入路对囊肿进行通气后,复发率高达60%。我们描述了复发性有症状PACG经鼻内镜治疗的技术细节,并对相关文献进行了综述。一名19岁女性因复发性右侧展神经麻痹就诊。四个月前,她接受了经鼻蝶窦手术(TSS)以引流有症状的PACG。目前的影像学检查证实右侧PACG复发。采用经蝶窦和岩下入路,以在岩尖获得更宽的骨性开口并引流囊肿。将一个多伊尔夹板插入囊肿腔内并延伸至蝶窦,在愈合过程中保持通畅。术后三个月,在内镜下取出夹板,可见两个通气腔之间有一个通畅的圆柱形通道。患者症状消失且未复发。内镜下经鼻手术必须进行调整以处理复发性PACG。单纯TSS可能不够。对于复发性PACG的治疗及预防复发,岩下入路、更宽的骨性开口、广泛切除囊肿前壁以及使用支架是必要的。