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在对超过 4 年的随访中,对于老年初级保健患者,存在主观记忆主诉的情况下,自感健康状况对永久性疗养院安置的预测价值。

The predictive value of self-rated health in the presence of subjective memory complaints on permanent nursing home placement in elderly primary care patients over 4-year follow-up.

机构信息

The Research Unit and Section of General Practice, Institute of Public Health, University of Copenhagen, Copenhagen, Denmark.

出版信息

Age Ageing. 2014 Jan;43(1):50-7. doi: 10.1093/ageing/aft131. Epub 2013 Aug 28.

DOI:10.1093/ageing/aft131
PMID:23985335
Abstract

BACKGROUND

self-rated health (SRH) predicts nursing home (NH) placement; subjective memory complaints (SMC) too. However, the predictive value of SRH in the presence of SMC is unclear.

METHODS

seven-hundred fifty-seven non-nursing home residents ≥65 years from general practices in Central Copenhagen were followed for 4 years (2002-2006). Patients gave information on SRH, cognition (SMC and MMSE), quality of life (EQ-5D) and socio-demographics. Information on comorbidities and permanent NH placement came from registries. The association between SRH (dichotomised into good versus poor) and SMC, and permanent NH placement was assessed using Cox proportional hazard regression adjusted for potential confounders.

RESULTS

NH placement totaled 6.5% at 4-year follow-up. Poor SRH increased NH placement [hazard ratio (HR) = 2.07, 95% CI: 1.11-3.87] adjusted for age, SMC, MMSE, sex and comorbidities. SRH was not associated with NH placement if accounting for additional health information; however, SMC was (HR = 2.47, 95% CI: 1.26-4.86). Increased placement was seen for patients with good SRH and SMC (HR = 6.64, 95% CI: 2.31-19.12), but not among patients with poor SRH and SMC (HR = 1.37, 95% CI: 0.59-3.20) when compared with the reference group (good SRH and without SMC).

CONCLUSIONS

both poor SRH and SMC were associated with permanent NH placement risk among elderly primary care patients. However, when SMC was present a reverse association was found for SRH: good SRH increased NH placement. Since SRH is integrated in widely used psychometric instruments, further research is needed to establish the mechanism and implications of this finding.

摘要

背景

自评健康(SRH)可预测养老院(NH)安置;主观记忆投诉(SMC)也是如此。然而,SRH 在存在 SMC 的情况下的预测价值尚不清楚。

方法

2002-2006 年,来自哥本哈根市中心的 757 名非养老院居民≥65 岁,在普通诊所接受了 4 年的随访。患者提供了关于 SRH、认知(SMC 和 MMSE)、生活质量(EQ-5D)和社会人口统计学的信息。来自登记处的信息包括合并症和永久性 NH 安置。使用 Cox 比例风险回归评估 SRH(分为良好和较差)与 SMC 和永久性 NH 安置之间的关联,并调整了潜在的混杂因素。

结果

4 年随访时,NH 安置总发生率为 6.5%。较差的 SRH 增加了 NH 安置的风险[风险比(HR)=2.07,95%置信区间:1.11-3.87],调整了年龄、SMC、MMSE、性别和合并症。如果考虑到其他健康信息,SRH 与 NH 安置无关;然而,SMC 有关(HR=2.47,95%置信区间:1.26-4.86)。在具有良好 SRH 和 SMC 的患者中,增加了安置的风险(HR=6.64,95%置信区间:2.31-19.12),但在具有较差 SRH 和 SMC 的患者中没有(HR=1.37,95%置信区间:0.59-3.20)与参考组(良好的 SRH 且无 SMC)相比。

结论

在老年初级保健患者中,较差的 SRH 和 SMC 均与永久性 NH 安置风险相关。然而,当 SMC 存在时,SRH 的关联就会逆转:良好的 SRH 增加了 NH 安置的风险。由于 SRH 已纳入广泛使用的心理计量学工具,因此需要进一步研究以确定这一发现的机制和影响。

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