Raushan A, Gaĭdarski R, Milkov V
Khirurgiia (Sofiia). 1990;43(2):33-6.
The present study was devoted to the still poorly exploited aspect of pancreas surgery, from a standpoint of postoperative divergences in the plasma prostaglandin level. Experiments were carried out with dogs. The authors apply proximal (right) resection of pancreas and eliminate the exocrine function of the remaining part by occlusion of the pancreatic canal. Radioimmunologic investigations were carried out by extraction method for determining the plasma thromboxane B2 level. Postoperative rise in TxB2 level was found. The authors apply modern drugs, proceeding from recent report in the literature about correction of this abnormality aimed at optimal re-establishment of the functions of the remaining pancreas after the operative intervention.
本研究从术后血浆前列腺素水平差异的角度,致力于探讨胰腺手术中仍未得到充分利用的方面。实验以狗为对象进行。作者实施胰腺近端(右侧)切除术,并通过阻塞胰管来消除剩余部分的外分泌功能。采用提取法进行放射免疫研究以测定血浆血栓素B2水平。发现术后TxB2水平升高。作者根据文献中关于纠正这种异常情况以在手术干预后最佳地重建剩余胰腺功能的最新报道,应用了现代药物。