Sala-Puigdollers A, Rodríguez-de la Rúa E, Saornil M A, García-Álvarez C, García-Lagarto E, Ovelar Arribas Y
Hospital Clínico Universitario de Valladolid, Universidad de Valladolid, Valladolid, España.
Arch Soc Esp Oftalmol. 2013 Sep;88(9):365-8. doi: 10.1016/j.oftal.2012.06.004. Epub 2012 Sep 15.
No intraocular biopsy technique is free of risk and all have the possibility of giving false negatives due to the difficulty in obtaining a sufficient sample. A modified chorioretinal biopsy was performed on a patient with suspected choroidal melanoma after negative biopsy with 25G vitrectomy. In addition to removing a solid fragment of tumor material using bimanual surgery, material from the lesion was obtained with the vitreotome to perform cytology, which confirmed the diagnosis of melanoma.
Cytology obtained through the vitreotome in association with removing a solid sample of the choroidal lesion may improve the efficiency of intraocular biopsy.
没有一种眼内活检技术是完全没有风险的，并且由于获取足够样本存在困难，所有技术都有可能出现假阴性结果。一名疑似脉络膜黑色素瘤的患者在25G玻璃体切割术活检结果为阴性后，接受了改良脉络膜视网膜活检。除了通过双手操作手术切除一块实性肿瘤组织外，还用玻璃体切割器获取病变组织进行细胞学检查，确诊为黑色素瘤。
通过玻璃体切割器获取的细胞学检查结果，结合切除脉络膜病变的实性样本，可能会提高眼内活检的效率。
