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一名服用华法林的患者发生急性非创伤性脊髓硬膜内血肿。

Acute nontraumatic spinal intradural hematoma in a patient on warfarin.

作者信息

Bruce-Brand Robert A, Colleran Gabrielle C, Broderick James M, Lui Darren F, Smith Eimear M, Kavanagh Eoin C, Poynton Ashley R

机构信息

Department of Trauma and Orthopaedic Surgery, Mater Misericordiae University Hospital, Dublin, Ireland.

出版信息

J Emerg Med. 2013 Nov;45(5):695-7. doi: 10.1016/j.jemermed.2013.04.048. Epub 2013 Aug 26.

Abstract

BACKGROUND

Nontraumatic spinal intradural extramedullary hematomas are extremely rare. When they occur, they can rapidly lead to spinal cord or cauda equina compression and have devastating consequences.

OBJECTIVE

The aim here was to report a case of this rare phenomenon and discuss the etiology, imaging, management, and outcome of intradural hematomas.

CASE REPORT

We describe the case of a 76-year-old man on warfarin therapy who presented with severe lower back pain and flaccid paraparesis. Blood tests revealed an international normalized ratio of 6.0. A magnetic resonance imaging result suggested an intradural hematoma extending from L1 to L4 and compressing the spinal cord and cauda equina. Emergency surgical decompression revealed an extensive intradural extramedullary hematoma, which was evacuated. The patient showed only minor neurologic improvement 6 months postoperatively.

CONCLUSIONS

Coagulopathy-induced spinal hemorrhage should be included in the differential diagnosis for patients presenting with signs of acute spinal cord compression.

摘要

背景

非创伤性脊髓硬膜内髓外血肿极为罕见。一旦发生,可迅速导致脊髓或马尾受压,并产生灾难性后果。

目的

本文旨在报告这一罕见现象的病例,并探讨硬膜内血肿的病因、影像学表现、治疗及预后。

病例报告

我们描述了一例正在接受华法林治疗的76岁男性患者,该患者出现严重的下背部疼痛和弛缓性截瘫。血液检查显示国际标准化比值为6.0。磁共振成像结果提示硬膜内血肿从L1延伸至L4,压迫脊髓和马尾。急诊手术减压显示广泛的硬膜内髓外血肿,予以清除。术后6个月,患者神经功能仅略有改善。

结论

对于出现急性脊髓受压体征的患者,鉴别诊断应包括凝血功能障碍引起的脊髓出血。

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