Ruhr University Eye Clinic, Bochum, Germany.
J Cataract Refract Surg. 2013 Sep;39(9):1314-20. doi: 10.1016/j.jcrs.2013.05.034.
To evaluate the efficacy of different treatment modalities in eyes with small pupils before femtosecond laser-assisted cataract surgery.
Ruhr University Eye Clinic, Bochum, Germany.
Prospective clinical trial.
Eyes with an intraoperative pupil size smaller than 5.5 mm received sequential treatments to achieve a pupil larger than 5.5 mm in 3 steps: (1) intracameral administration of epinephrine solution, (2) additional viscomydriasis, and (3) implantation of a Malyugin ring pupil expander. When a step enlarged the pupil to at least 5.5 mm, femtosecond laser-assisted cataract surgery with an anterior capsulotomy diameter of at least 4.5 mm and 350 μm nuclear fragmentation grids, ultrasound phacoemulsification, and intraocular lens implantation were performed. Main outcome measures were achieved preoperative pupil size in each sequential treatment group and analysis of intraoperative complications.
Of 850 eyes scheduled for cataract surgery, 40 received sequential treatments. To achieve a pupil larger than 5.5 mm, epinephrine was sufficient in 7% of the eyes; additional viscomydriasis was necessary in 25%, and the pupil expander was implanted in 68%. The most frequent comorbidities were pseudoexfoliation of the lens capsule (30.0%) and intraoperative floppy-iris syndrome (12.5%). Tongue-like lesions of the capsulotomies were detected in 5 eyes.
The 3-step treatment allowed the surgeon to increase the efficiency and safety of femtosecond-assisted cataract surgery in eyes with a small preoperative pupil, providing good safety margins at the pupil boundary for the capsulotomy and the softened nuclear volume.
评估飞秒激光辅助白内障手术前小瞳孔眼不同治疗方式的疗效。
德国波鸿鲁尔大学眼科诊所。
前瞻性临床试验。
术中瞳孔小于 5.5mm 的眼接受序贯治疗,分 3 步使瞳孔扩大至 5.5mm 以上:(1)房内给予肾上腺素溶液;(2)进一步行黏弹剂扩瞳;(3)植入 Malyugin 环瞳孔扩张器。当某一步使瞳孔扩大至至少 5.5mm 时,行飞秒激光辅助白内障手术,截囊直径至少 4.5mm,核碎 350μm 网格,超声乳化吸除白内障,植入人工晶状体。主要观察指标为每个序贯治疗组的术前瞳孔大小和术中并发症分析。
850 例行白内障手术的眼中,40 眼接受序贯治疗。为使瞳孔扩大至 5.5mm 以上,肾上腺素组成功率为 7%;需进一步行黏弹剂扩瞳者占 25%,植入瞳孔扩张器者占 68%。最常见的合并症为晶状体囊膜的假性剥脱(30.0%)和术中虹膜松软综合征(12.5%)。5 眼发现囊切开处有舌状病变。
三步治疗法可提高术者在小瞳孔前行飞秒辅助白内障手术的效率和安全性,为截囊和软化核体积提供了良好的瞳孔边界安全裕度。