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[妊娠与炎性风湿性疾病]

[Pregnancy and inflammatory rheumatic diseases].

作者信息

Fischer-Betz R, Späthling-Mestekemper S

机构信息

Poliklinik für Rheumatologie, Heinrich Heine Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland,

出版信息

Z Rheumatol. 2013 Sep;72(7):669-82. doi: 10.1007/s00393-013-1223-9.

DOI:10.1007/s00393-013-1223-9
PMID:23989692
Abstract

Pregnancy in women with rheumatic diseases represents a challenge for patients and physicians and requires optimal shared decision-making strategies. However, the majority of women can have a successful pregnancy and the vast majority of babies are born healthy. Specific preconception care should be offered to women with rheumatic diseases to optimize and increase the chances of a successful pregnancy. A careful assessment of possible risks and the justified use of antirheumatic drugs before, during and after pregnancy are key issues.

摘要

患有风湿性疾病的女性怀孕对患者和医生来说都是一项挑战,需要最佳的共同决策策略。然而,大多数女性能够成功怀孕,并且绝大多数婴儿健康出生。应为患有风湿性疾病的女性提供特定的孕前护理,以优化并增加成功怀孕的几率。在怀孕前、期间和之后仔细评估可能的风险以及合理使用抗风湿药物是关键问题。

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Rheumatology (Oxford). 2013 Jun;52(6):1070-6. doi: 10.1093/rheumatology/kes425. Epub 2013 Feb 4.
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The effect of vitamin D supplementation on inflammatory and hemostatic markers and disease activity in patients with systemic lupus erythematosus: a randomized placebo-controlled trial.
维生素 D 补充对系统性红斑狼疮患者炎症和止血标志物及疾病活动的影响:一项随机安慰剂对照试验。
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Impact of TNF-blocking agents on male sperm characteristics and pregnancy outcomes in fathers exposed to TNF-blocking agents at time of conception.在受孕时接触 TNF 阻滞剂的父亲的 TNF 阻滞剂对男性精子特征和妊娠结局的影响。
Clin Exp Rheumatol. 2012 Sep-Oct;30(5):765-7. Epub 2012 Oct 17.
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Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis.欧洲抗风湿病联盟和欧洲肾脏协会-欧洲透析和移植协会(EULAR/ERA-EDTA)成人和儿童狼疮肾炎管理建议。
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Second pregnancy outcomes for women with systemic lupus erythematosus.系统性红斑狼疮女性的第二次妊娠结局。
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Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus.羟氯喹的使用与降低新生儿狼疮中抗 SSA/Ro 抗体相关的复发性心脏表现的风险相关。
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Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited.重新审视维生素D缺乏和不足的防治指南。
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Effects of infertility, pregnancy loss, and patient concerns on family size of women with rheumatoid arthritis and systemic lupus erythematosus.不孕、流产和患者关注对类风湿关节炎和系统性红斑狼疮女性家庭规模的影响。
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Impact of previous lupus nephritis on maternal and fetal outcomes during pregnancy.狼疮肾炎对妊娠期间母婴结局的影响。
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