Pliatsko V V, Levenets V N, Stavinskiĭ Iu A
Ortop Travmatol Protez. 1990 May(5):24-8.
The authors have determined the changes in the synovial medium of the joint characteristic of various stages of severity of the disease in 248 patients with deforming gonarthrosis on the basis of arthroscopic and thermographic studies and investigation of the permeability of the synovial membrane in the complex with clinical and roentgenologic examinations. At the initial stages the signs of local reactive inflammation of the synovial membrane near the foci of degeneration of the articular cartilage prevail. For the late stages a trend to spreading of the reactive inflammation of the synovial membrane with the development of sclerotic changes in the previously affected areas is characteristic. A comparison of the results of arthroscopy, infra-red thermography and the permeability of the synovial membrane point at parallel changes in the synovial medium and in the microcirculatory and regional circulation of the knee joint. These findings may be used for working out the rational tactics of treatment of the patients with deforming gonarthrosis.
作者基于关节镜检查、热成像研究以及滑膜通透性研究，并结合临床和X线检查，确定了248例变形性膝关节炎患者疾病不同严重程度阶段关节滑膜介质的变化。在疾病初期，关节软骨退变部位附近滑膜局部反应性炎症的体征较为常见。在疾病后期，滑膜反应性炎症有扩散趋势，且先前受累区域会出现硬化改变。关节镜检查、红外热成像检查结果以及滑膜通透性的比较表明，滑膜介质以及膝关节微循环和局部循环存在平行变化。这些发现可用于制定变形性膝关节炎患者的合理治疗策略。
