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一种具有深穿透深度的电磁热疗系统,用于经皮热消融。

An electromagnetic thermotherapy system with a deep penetration depth for percutaneous thermal ablation.

机构信息

Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan.

出版信息

Ann Biomed Eng. 2014 Jan;42(1):86-96. doi: 10.1007/s10439-013-0899-y. Epub 2013 Aug 29.

Abstract

Thermal ablation has been a promising method to remove the cancerous tissues. Electromagnetic-based thermotherapy has been extensively investigated for a variety of medical applications recently. In this study, a prototype electromagnetic thermotherapy system has been developed with a new coil design and a two-section needle. The coil can generate an alternating electromagnetic field (EMF) with a deep penetration depth to remotely heat the needle which is located up to 15 cm away, enabling percutaneous thermal ablation. Several important parameters, including the heating effects of the needle at different positions, the intensity of the EMF and the induced temperature distribution on the surrounding tissue, are first explored. An in vitro animal experiment has also been performed which shows EMF-induced ablation in a porcine liver by the needle. Furthermore, an in vivo experiment on an animal model (a New Zealand white rabbit) is also conducted in the study. Thus, the two-section needle combined with the coil-generated EMF has been demonstrated to be a promising thermotherapy system for percutaneous thermal ablation.

摘要

热消融技术是一种有前途的方法,可以去除癌变组织。最近,基于电磁的热疗已经被广泛应用于各种医学领域。在这项研究中,开发了一种带有新型线圈设计和两段式针的电磁热疗系统原型。该线圈能够产生具有深穿透深度的交变电磁场 (EMF),从而可以对位于最远 15 厘米处的针进行远程加热,实现经皮热消融。首先探索了几个重要参数,包括不同位置的针的加热效果、电磁场的强度以及周围组织的感应温度分布。该研究还进行了一项离体动物实验,结果显示通过针进行的猪肝脏的电磁场诱导消融。此外,在动物模型(新西兰白兔)上还进行了一项体内实验。因此,两段式针与线圈产生的 EMF 相结合,已被证明是一种有前途的经皮热消融热疗系统。

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