Aung Aye, Alqudihy Shukri, Rybicki Lisa, Platt Alexandra, Davis Mellar P
Palliative Medicine and Supportive Oncology Services, Taussig Cancer Institute, Cleveland, OH, USA.
Palliative Medicine and Supportive Oncology Services, Taussig Cancer Institute, Cleveland, OH, USA Cleveland Clinic Lerner School of Medicine, Case Western Reserve University, Cleveland, OH, USA Cleveland Clinic Palliative Medicine Clinical Fellowship Program, Cleveland clinic, Cleveland, OH, USA
Am J Hosp Palliat Care. 2014 Dec;31(8):862-6. doi: 10.1177/1049909113501851. Epub 2013 Aug 28.
Low creatinine and albumin are found among the chronically ill patients. This study retrospectively reviewed albumin and creatinine levels for survival in patients upon admission.
Records of patients admitted over 2 months were reviewed. Recursive partitioning analysis (RPA) identified cutpoints in albumin and creatinine that predicted survival. Kaplan-Meier survival, Cox proportional hazards, and stepwise Cox analyses identified prognostic factors.
Of 83 patients, 81 were assessable. Variables for worse survival were albumin <3.1 g/dL, creatinine >0.93 mg/dL, and male gender. Albumin by continuous, median, RPA, and tertiles was significant; creatinine by RPA. Hazard ratio for albumin >3.1 was 0.28 (P < .001) and for creatinine >0.91 mg/dL was 1.8 (P = .046).
Albumin and creatinine are prognostically important.
