Departments of Cardiology, Ataturk Education and Research Hospital, Yıldırım Beyazıt University, Ankara, Turkey.
Int J Rheum Dis. 2013 Aug;16(4):425-9. doi: 10.1111/1756-185X.12049. Epub 2013 Apr 4.
In our study, we aimed to evaluate left ventricular function in patients with Sjögren syndrome (SS) using tissue Doppler echocardiography (TDE) and myocardial performance index (MPI) in addition to conventional echocardiographic methods.
We evaluated 50 patients with SS and 48 healthy volunteers with similar demographic characteristics. Systolic and diastolic functions of the left ventricle were analyzed with standard two-dimensional (2D) echocardiography, M-mode echocardiography, pulsed-wave (PW) Doppler and tissue Doppler imaging.
Septal part of the mitral annulus PW TDE showed that systolic myocardial wave (Sm), early diastolic myocardial wave (Em), late diastolic myocardial wave (Am) and Em/Am ratios are significantly lower, and myocardial isovolumetric relaxation time (IVRTm) and MPI values are significantly higher in patients with SS. Lateral site of the mitral annulus PW TDE showed that Em, Sm and Em/Am ratios are significantly lower, and IVRTm and MPI values are significantly higher in patients with SS compared with healthy controls.
In this study, it was shown that both left ventricle systolic and diastolic functions of patients with SS were disturbed.
在我们的研究中，除了常规超声心动图方法外，我们还使用组织多普勒超声心动图（TDE）和心肌做功指数（MPI）来评估干燥综合征（SS）患者的左心室功能。
我们评估了 50 例 SS 患者和 48 例具有相似人口统计学特征的健康志愿者。使用标准二维（2D）超声心动图、M 型超声心动图、脉冲波（PW）多普勒和组织多普勒成像分析左心室的收缩和舒张功能。
二尖瓣环 PW TDE 的间隔部分显示，SS 患者的收缩期心肌波（Sm）、早期舒张期心肌波（Em）、晚期舒张期心肌波（Am）和 Em/Am 比值明显降低，等容舒张时间（IVRTm）和 MPI 值明显升高。二尖瓣环 PW TDE 的侧壁部分显示，与健康对照组相比，SS 患者的 Em、Sm 和 Em/Am 比值明显降低，IVRTm 和 MPI 值明显升高。
本研究表明 SS 患者的左心室收缩和舒张功能均受到干扰。
