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[过敏性肺泡炎还是特发性哮喘?(病例报告)]

[Allergic alveolitis or intrinsic asthma? (A case report)].

作者信息

Kneussl M, Czernin J, Mlczoch J, Kummer F

机构信息

Kardiologische Universitätsklinik Wien.

出版信息

Pneumologie. 1990 Jul;44(7):910-2.

PMID:2399243
Abstract

We report on a 37-year old patient with a simple viral infection who presented with acute bronchitis with bronchospasm, a productive cough and severe dyspnoea. Because of his specific occupational history--the patient is a forester and was exposed to wood dust and fungi--he was at high risk for extrinsic allergic alveolitis with mucoid impaction, so that the cause of hypoxemia and cyanosis was obvious. Repeated immunological parameters including gel-precipitations were negative: The lung function pattern (reduced vital capacity, a reduced FEV1, reduced flow values at low vital capacity and with the characteristic shape of the flow volume-curve but normal airway-resistance) suggested the diagnosis of intrinsic asthma limited to the small airways - "bronchiolar asthma" - severe small airway disease.

摘要

我们报告了一名37岁患有单纯病毒感染的患者,其表现为伴有支气管痉挛的急性支气管炎、咳痰性咳嗽和严重呼吸困难。鉴于其特殊的职业史——该患者是一名林业工人,接触过木屑和真菌——他患伴有黏液嵌塞的外源性过敏性肺泡炎的风险很高,因此低氧血症和发绀的病因很明显。包括凝胶沉淀法在内的多项免疫学指标均为阴性:肺功能模式(肺活量降低、第一秒用力呼气容积降低、低肺活量时流量值降低且流量-容积曲线呈特征性形状但气道阻力正常)提示诊断为局限于小气道的内源性哮喘——“细支气管哮喘”——严重的小气道疾病。

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