Kim Young Bin, Leem Dae Ho, Baek Jin A, Ko Seung O
Clinical Fellow, Department of Oral and Maxillofacial Surgery, School of Dentistry, Chonbuk National University, Jeonju, Republic of Korea.
Associate Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Chonbuk National University, Jeonju, Republic of Korea.
J Oral Maxillofac Surg. 2014 Feb;72(2):431-9. doi: 10.1016/j.joms.2013.06.222. Epub 2013 Aug 29.
Liposarcoma, first described by Virchow in 1857, is a common mesenchymal malignant tumor arising from the adipose tissue. The most common of all soft tissue sarcomas, liposarcomas account for approximately 20% of all soft tissue sarcomas. However, it is rare in the head and neck, particularly in the oral cavity. Oral liposarcomas have been reported to occur mainly on the buccal mucosa, with other sites including the floor of the mouth, tongue, palate, and mandible. However, almost no cases of a liposarcoma located on the gingiva have been reported. To our knowledge, only 5 cases of liposarcoma of the gingiva have been previously reported in English language studies. We present a rare case of an atypical lipomatous tumor/well-differentiated liposarcoma of the gingiva of the anterior mandible that occurred in a 77-year-old male patient. Our patient underwent surgical excision and alveolar decortication. We also present a review of the current published data. At 18 months of follow-up, the patient remained free of disease.
脂肪肉瘤由维尔肖于1857年首次描述,是一种常见的起源于脂肪组织的间叶性恶性肿瘤。脂肪肉瘤是所有软组织肉瘤中最常见的类型,约占所有软组织肉瘤的20%。然而,它在头颈部很少见,尤其是在口腔。据报道,口腔脂肪肉瘤主要发生于颊黏膜,其他部位包括口底、舌、腭和下颌骨。然而,几乎没有位于牙龈的脂肪肉瘤病例报道。据我们所知,英文研究中此前仅报道过5例牙龈脂肪肉瘤。我们报告1例罕见的非典型脂肪瘤性肿瘤/高分化脂肪肉瘤,发生于1例77岁男性患者的下颌前部牙龈。我们的患者接受了手术切除和牙槽骨皮质剥除术。我们还对当前已发表的数据进行了综述。随访18个月时,患者无疾病复发。