Capodiferro S, Scully C, Maiorano E, Lo Muzio L, Favia G
Department of Dental Sciences and Surgery, University of Bari, Bari, Italy.
Oral Dis. 2004 Nov;10(6):398-400. doi: 10.1111/j.1601-0825.2004.01040.x.
Liposarcoma, first described by Virchow in 1857, is the second most frequent sarcoma of soft tissues, although it is rare both in the head and neck and the oral cavity. Intra-orally, liposarcoma has been reported in the jawbones (particularly the maxilla) and the soft tissues -- mainly the cheek and floor of mouth, but it is rare in the tongue. A case of well-differentiated, superficial liposarcoma circumscriptum of the tongue is reported. The authors underline the difficulties in the clinical and histopathological diagnosis, as this tumour may be confused with lipoma. In view of the indolent behaviour of this tumour type, local recurrence or metastasis rarely occur; consequently, conservative surgical therapy is advised without adjuvant chemo-radio therapy.
脂肪肉瘤于1857年由魏尔啸首次描述,是第二常见的软组织肉瘤,尽管在头颈部和口腔中都很罕见。在口腔内,脂肪肉瘤已见诸报道,发生于颌骨(尤其是上颌骨)和软组织——主要是颊部和口底,但在舌部罕见。本文报告一例舌部高分化浅表局限性脂肪肉瘤病例。作者强调了临床和组织病理学诊断中的困难,因为这种肿瘤可能与脂肪瘤混淆。鉴于这种肿瘤类型的惰性行为,很少发生局部复发或转移;因此,建议采用保守手术治疗,无需辅助放化疗。