Brown F W, Golding J M, Smith G R
Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock 72205.
Psychosom Med. 1990 Jul-Aug;52(4):445-51. doi: 10.1097/00006842-199007000-00006.
Lifetime prevalence rates were calculated for comorbid psychiatric disorders in 119 patients who were referred from primary care physicians for unexplained somatic complaints and who met DSM III-R criteria for somatization disorder. Comparisons were made with general population norms from the ECA study. Prevalence of nine comorbid conditions was significantly higher than in the general populations. The most prevalent comorbid diagnoses were major depression (54.6%), generalized anxiety disorder (33.6%), and phobic disorders (31.1%). The least common comorbid disorders were mania (4.2%) and drug abuse (4.9%); drug abuse prevalence rates did not significantly exceed general population estimates. Risk ratios were highest for panic disorder (16.25), major depression (9.41), schizophrenia (7.77), and obsessive-compulsive disorder (7.04).
对119名因不明原因躯体不适而由初级保健医生转诊且符合《精神疾病诊断与统计手册》第三版修订版（DSM III-R）躯体化障碍标准的患者，计算其共病精神障碍的终生患病率。并与流行病学集区（ECA）研究中的普通人群规范进行比较。九种共病情况的患病率显著高于普通人群。最常见的共病诊断是重度抑郁症（54.6%）、广泛性焦虑症（33.6%）和恐惧症（31.1%）。最不常见的共病障碍是躁狂症（4.2%）和药物滥用（4.9%）；药物滥用的患病率未显著超过普通人群的估计值。惊恐障碍（16.25）、重度抑郁症（9.41）、精神分裂症（7.77）和强迫症（7.04）的风险比最高。
