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深低温停循环:现实生活中的假死。

Deep hypothermic circulatory arrest: real-life suspended animation.

机构信息

Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

出版信息

Prog Cardiovasc Dis. 2013 Jul-Aug;56(1):81-91. doi: 10.1016/j.pcad.2013.05.009.

DOI:10.1016/j.pcad.2013.05.009
PMID:23993241
Abstract

Deep hypothermic circulatory arrest (DHCA) is a cerebral protection technique that was developed in the 1950s and popularized in the 1970s. It has become one of the three most common cerebral protection techniques currently used in aortic arch surgeries, with the other two being antegrade cerebral perfusion (ACP) and retrograde cerebral perfusion (RCP). At our institution, DHCA has been the cerebral protection technique of choice for over a quarter century. Our clinical experience with DHCA has been very positive, and our clinical studies have shown DHCA to have outcomes equal to (and sometimes better than) those of ACP and RCP, and DHCA to be very effective at preserving neurocognitive function. Other institutions, however, prefer ACP or RCP to DHCA. Each technique has its own set of pros and cons, and the question regarding which technique is the superior method for cerebral protection is hotly debated.

摘要

深低温停循环(DHCA)是一种脑保护技术,于 20 世纪 50 年代发展起来,并于 20 世纪 70 年代普及。它已成为目前主动脉弓手术中最常用的三种脑保护技术之一,另外两种是顺行性脑灌注(ACP)和逆行性脑灌注(RCP)。在我们机构,DHCA 作为脑保护技术已经使用了二十五年以上。我们使用 DHCA 的临床经验非常积极,我们的临床研究表明,DHCA 的结果与 ACP 和 RCP 相当(有时甚至更好),并且在保护神经认知功能方面非常有效。然而,其他机构更倾向于使用 ACP 或 RCP 而不是 DHCA。每种技术都有其自身的优缺点,关于哪种技术是脑保护的优越方法的问题存在激烈的争论。

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