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乳腺癌皮肤转移:一种罕见变异型的简要报告及形态学分类建议

Cutaneous Metastasis from Breast Carcinoma: a brief report of a rare variant and proposed morphological classification.

作者信息

Chisti M A, Alfadley A A, Banka N, Ezzat A

机构信息

Muzamil A. Chisti, MD, Department of Dermatology, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh 11211, Kingdom of Saudi Arabia, Tel. +966 1 442 4608, Fax No. +966 1 442 4603, Email:

出版信息

Gulf J Oncolog. 2013 Jul;1(14):90-4.

Abstract

BACKGROUND

Breast carcinoma is the second commonest cancer in women after non-melanoma skin cancers and, excluding melanoma, the most common tumor to metastasize to the skin in women. Cutaneous metastasis from breast cancer has varied presentations but there is no well-established classification which includes them all.

OBJECTIVE AND CONCLUSION

We report a 69 year-old lady with advanced primary ductal carcinoma of right breast (cT4cN1cM0) who presented five months after radical mastectomy with very extensive cutaneous metastases in absence of distant spread. Skin involvement was in the form of nodules and purpuric papulo-vesicles on a background of erythema which clinically mimicked lymphatic malformation. We also propose a morphological classification of the cutaneous metastasis from breast cancer.

KEYWORDS

Breast Carcinoma, Cutaneous metastasis, lymphatic malformation.

摘要

背景

乳腺癌是女性继非黑色素瘤皮肤癌之后第二常见的癌症,并且在排除黑色素瘤的情况下,是女性中最常转移至皮肤的肿瘤。乳腺癌的皮肤转移表现多样,但尚无一个涵盖所有表现的完善分类。

目的与结论

我们报告了一位69岁女性,患有右乳晚期原发性导管癌(cT4cN1cM0),在根治性乳房切除术后五个月出现,有非常广泛的皮肤转移且无远处转移。皮肤受累表现为在红斑背景上出现结节和紫癜性丘疹水疱,临床上酷似淋巴管畸形。我们还提出了乳腺癌皮肤转移的形态学分类。

关键词

乳腺癌;皮肤转移;淋巴管畸形

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