Starczewska Małgorzata H, Wawrzyńska Liliana, Opoka Lucyna, Małek Grzegorz, Wieliczko Monika, Amatuszkiewicz-Rowińska Joanna, Szturmowicz Monika
II Klinika Anestezjologii i Intensywnej Terapii, Centralny Szpital Kliniczny, Warszawski Uniwersytet Medyczny, ul. Banacha 1a, Warsaw.
Pneumonol Alergol Pol. 2013;81(5):460-7.
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that is characterized by its chronic course and the involvement of many organs and systems. The most common abnormality in the respiratory system of SLE patients is lupus pleuritis. Less common is parenchymal involvement, which may present as acute lupus pneumonitis (ALP) or chronic interstitial lung disease. Other possible pulmonary manifestations of SLE include pulmonary embolism, diffuse alveolar haemorrhage, acute reversible hypoxaemia, and shrinking lung syndrome. We present the case report of a young woman with previously diagnosed membranous glomerulonephritis with nephrotic syndrome and antiphospholipid syndrome, who was admitted with marked of shortness of breath. The diagnostic process, including imaging studies and laboratory tests, enabled us to confirm a diagnosis of ALP. After initiation of treatment with high doses of methyloprednisolone, nearly complete remission of pulmonary changes was observed. We also perform a literature review regarding acute lupus pneumonitis.
系统性红斑狼疮(SLE)是一种自身免疫性结缔组织病,其特点是病程慢性且累及多个器官和系统。SLE患者呼吸系统最常见的异常是狼疮性胸膜炎。实质受累较少见,可表现为急性狼疮性肺炎(ALP)或慢性间质性肺病。SLE其他可能的肺部表现包括肺栓塞、弥漫性肺泡出血、急性可逆性低氧血症和肺萎陷综合征。我们报告一例先前诊断为膜性肾小球肾炎伴肾病综合征和抗磷脂综合征的年轻女性病例,该患者因明显气短入院。包括影像学检查和实验室检查在内的诊断过程使我们能够确诊为ALP。在开始使用大剂量甲泼尼龙治疗后,观察到肺部病变几乎完全缓解。我们还对急性狼疮性肺炎进行了文献综述。